268R-1

IgD (EP173) Rabbit Monoclonal Primary Antibody

• UNSPSC 코드: 12352203
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100; 500
• 결합: unconjugated
• 항체 형태: culture supernatant
• 항체 생산 유형: primary antibodies
• 클론: EP173, monoclonal
• 설명: (For In Vitro Diagnostic Use in Select Regions (See Chart))
• 양식: buffered aqueous solution
• 종 반응성: human
• 포장: bottle of 1.0 mL predilute (268R-17); bottle of 7.0 mL predilute (268R-18); vial of 0.1 mL concentrate (268R-14); vial of 0.5 mL concentrate (268R-15); vial of 1.0 mL concentrate (268R-16)
• 제조업체/상표: Cell Marque^®
• 기술: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100
• 동형: IgG
• 배송 상태: wet ice
• 저장 온도: 2-8°C

설명

일반 설명

The monoclonal antibody against IgD reacts with immunoglobin D delta chains. In tonsil and lymph node, immunohistochemical staining for IgD immunoglobulin heavy chain is usually used to highlight the tonsil and nodal architecture since the IgD antibody stains mantle zone cells in secondary follicles and mantle cells in primary follicles.¹ It has been reported that IgD can be detected in the surface/cytoplasm of neoplastic cells of common small B lymphoid cell lymphomas, such as small lymphocytic lymphoma, mantle cell lymphoma, marginal zone lymphoma (especially splenic marginal zone lymphoma), and follicular lymphoma.^1-2 IgD expression in L & P cells of nodular lymphocyte predominant Hodkin lymphoma has been seen in subsets of cases (27% to 71.4%).^1-3 The IgD positive L & P cells are usually located in the extrafollicular area with a relatively T-cell-rich background^1,3 IgD expression is rarely seen in T-cell rich B-cell lymphoma. Studies have demonstrated that Reed-Sternberg cells of classic Hodgkin lymphoma were negative for IgD^1,3 IgD multiple myeloma is a rare bone marrow plasma cell dyscrasia and can be identified by the IgD antibody, especially when a dry tap is encountered.⁴

품질

IVD

IVD

IVD

RUO

결합

IgD Positive Control Slides, Product No. 268S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

제조 메모

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

기타 정보

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

법적 정보

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable