추천 제품
생물학적 소스
rabbit
Quality Level
100
500
결합
unconjugated
항체 형태
culture supernatant
항체 생산 유형
primary antibodies
클론
SP17, monoclonal
설명
For In Vitro Diagnostic Use in Select Regions (See Chart)
형태
buffered aqueous solution
종 반응성
human
포장
vial of 0.1 mL concentrate (229R-14)
vial of 0.5 mL concentrate (229R-15)
bottle of 1.0 mL predilute (229R-17)
vial of 1.0 mL concentrate (229R-16)
bottle of 7.0 mL predilute (229R-18)
제조업체/상표
Cell Marque™
기술
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
동형
IgG
제어
medullary carcinoma of thyroid
배송 상태
wet ice
저장 온도
2-8°C
시각화
cytoplasmic
일반 설명
Calcitonin (thyrocalcitonin) is a 32 amino acid linear polypeptide hormone that is involved in regulating calcium metabolism. It is primarily produced by the parafollicular cells (also known as C cells) of the thyroid gland, though some neuroendocrine cells in other tissues, such as the respiratory and digestive tracts, can also synthesize calcitonin. Anti-calcitonin immunohistochemistry is an effective way for demonstrating the parafollicular C cells in the thyroid3,4 and the tumors arising from them, including C cell hyperplasia of the thyroid and medullary thyroid carcinoma, a neuroendocrine tumor that originates from C cells.
Immunohistochemical staining with anti-calcitonin antibody has proven to be an effective way of demonstrating calcitonin-producing cells in the thyroid. C-cell hyperplasia and medullary thyroid carcinomas stain positive for calcitonin. Studies of calcitonin have resulted in the identification of a wide spectrum of C-cell proliferative abnormalities. citationcitationcitationcitationcitation
Immunohistochemical staining with anti-calcitonin antibody has proven to be an effective way of demonstrating calcitonin-producing cells in the thyroid. C-cell hyperplasia and medullary thyroid carcinomas stain positive for calcitonin. Studies of calcitonin have resulted in the identification of a wide spectrum of C-cell proliferative abnormalities. citationcitationcitationcitationcitation
품질
 IVD |  IVD |  IVD |  RUO |
결합
Calcitonin Positive Control Slides, Product No. 229S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
물리적 형태
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide
제조 메모
Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.
기타 정보
For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com
법적 정보
Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany
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시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Plasma-immunoreactive-calcitonin in patients with non-thyroid tumours.
R C Coombes et al.
Lancet (London, England), 1(7866), 1080-1083 (1974-06-01)
Evidence for calcitonin--a new hormone from the parathyroid that lowers blood calcium.
D H COPP et al.
Endocrinology, 70, 638-649 (1962-05-01)
Y Dayal et al.
Cancer, 43(4), 1331-1338 (1979-04-01)
A nonfunctioning strumal carcinoid arising in a 49-year-old woman was studied by histochemical and immunocytochemical techniques. All tumor cells, irrespective of their architectural arrangement, showed properties of neuroendocrine-programmed cells, without any evidence of thyroid follicular cell differentiation. Foci of calcitonin-producing
Calcitonin and carcinoembryonic antigen as tumor markers in medullary thyroid carcinoma.
R A DeLellis et al.
American journal of clinical pathology, 70(4), 587-594 (1978-10-01)
Y Kameda et al.
Cell and tissue research, 206(3), 403-415 (1980-01-01)
The development of C-cell complexes was investigated in dog fetuses by an immunoperoxidase method with three specific antisera: anti-calcitonin, anti-C-thyroglobulin (C-Tg), and anti-19S thyroglobulin. Ultimobranchial bodies joined with the thyroid anlage and then dispersed into the parenchyma to form large
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