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Merck
모든 사진(1)

Key Documents

226R-1

Sigma-Aldrich

BCL2 (E17) Rabbit Monoclonal Primary Antibody

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About This Item

UNSPSC 코드:
12352203
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

100
500

결합

unconjugated

항체 형태

culture supernatant

항체 생산 유형

primary antibodies

클론

E17, monoclonal

설명

For In Vitro Diagnostic Use in Select Regions (See Chart)

형태

buffered aqueous solution

종 반응성

human

포장

vial of 0.1 mL concentrate (226R-14)
vial of 0.5 mL concentrate (226R-15)
bottle of 1.0 mL predilute (226R-17)
vial of 1.0 mL concentrate (226R-16)
bottle of 7.0 mL predilute (226R-18)

제조업체/상표

Cell Marque

기술

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100

동형

IgG

제어

tonsil

배송 상태

wet ice

저장 온도

2-8°C

시각화

cytoplasmic

유전자 정보

human ... BCL2(596)

일반 설명

Anti-BCL2 has shown consistent negative reaction on reactive germinal centers and positive staining of neoplastic follicles in follicular lymphoma. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. This antibody may also be used in distinguishing between those follicular lymphomas that express BCL2 protein and the small number in which the neoplastic cells are BCL2 negative.

결합

BCL2 Positive Control Slides, Product No. 226S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

물리적 형태

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

제조 메모

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

기타 정보

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

법적 정보

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

B Martin et al.
British journal of cancer, 89(1), 55-64 (2003-07-03)
The role of the anti-apoptotic protein Bcl-2 in lung cancer remains controversial. In order to clarify its impact on survival in small and non-small cell lung cancer (NSCLC), we performed a systematic review of the literature. Trials were selected for
J W Moul
European urology, 35(5-6), 399-407 (1999-05-15)
Within the past 5 years, research has increasingly addressed molecular alterations in prostate cancer (CaP). Mutations of tumor suppressor gene p53 have been found in a variety of cancers, including urologic neoplasms. Several studies have been conducted on CaP specimens
D R Ciocca et al.
Endocrine, 13(1), 1-10 (2000-10-29)
Tamoxifen is one of the most effective treatments for breast cancer. Standard practice is to select patients who are likely to respond to this therapy through the evaluation of estrogen receptor (ER) and progesterone receptor (PR) in the primary tumor
M L Cleary et al.
Cell, 47(1), 19-28 (1986-10-10)
cDNAs for the bcl-2 mRNA were cloned from a human common acute lymphoblastic leukemia cell line. Nucleotide sequence analyses showed that the 6 kb bcl-2 mRNA potentially encodes a 26 kd protein that is homologous to a predicted Epstein-Barr virus
D Hockenbery et al.
Nature, 348(6299), 334-336 (1990-11-22)
The t(14; 18) chromosomal translocation of human follicular B-cell lymphoma juxtaposes the bcl-2 gene with the immunoglobulin heavy chain locus. The bcl-2 immunoglobulin fusion gene is markedly deregulated resulting in inappropriately elevated levels of bcl-2 RNA and protein. Transgenic mice

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