모든 사진(1)
About This Item
실험식(Hill 표기법):
C17H21N3O4S
CAS Number:
Molecular Weight:
363.43
Beilstein:
50100
MDL number:
UNSPSC 코드:
12352106
eCl@ss:
34058011
PubChem Substance ID:
NACRES:
NA.79
추천 제품
분석
≥98.0% (HPLC)
형태
powder
광학 활성
[α]20/D +55±3°, c = 0.5% in 0.1 M NaOH
색상
white to light yellow
mp
295-297 °C
저장 온도
2-8°C
SMILES string
[H][C@]12CS[C@@H](CCCCC(=O)Nc3ccc(cc3)C(O)=O)[C@@]1([H])NC(=O)N2
InChI
1S/C17H21N3O4S/c21-14(18-11-7-5-10(6-8-11)16(22)23)4-2-1-3-13-15-12(9-25-13)19-17(24)20-15/h5-8,12-13,15H,1-4,9H2,(H,18,21)(H,22,23)(H2,19,20,24)/t12-,13-,15-/m0/s1
InChI key
PVMDAMXGKHIMSQ-YDHLFZDLSA-N
생화학적/생리학적 작용
Biotinyl-4-aminobenzoic acid (B-PABA) is used as a substrate in biotinidase assays.
기타 정보
Enzyme substrate used in the assay of biotinidase
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
개인 보호 장비
Eyeshields, Gloves, type N95 (US)
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
이미 열람한 고객
Determination of biotinidase activity by liquid chromatography with fluorimetric detection.
K Hayakawa et al.
Journal of chromatography, 383(1), 148-152 (1986-11-28)
D V Craft et al.
Biochemistry, 24(10), 2471-2476 (1985-05-07)
Biotinidase catalyzes the hydrolysis of N epsilon-biotinyllysine (biocytin) to form biotin and free lysine. The enzyme has been purified 4800-fold from outdated human plasma and was determined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis to have a molecular weight of (76
Keyna A Kobza et al.
The Journal of nutritional biochemistry, 19(12), 826-832 (2008-05-16)
Posttranslational modification of histones by biotinylation can be catalyzed by both biotinidase (BTD) and holocarboxylase synthetase. Biotinylation of histones is an important epigenetic mechanism to regulate gene expression, DNA repair, and chromatin remodeling. The role of BTD in histone biotinylation
D T Forman et al.
Annals of clinical and laboratory science, 22(3), 144-154 (1992-05-11)
Children with juvenile-onset multiple carboxylase deficiency lack biotinidase activity (biotinamide amidohydrolase, EC 3.5.1.12) in the liver and other tissues. Hence, little free biotin is metabolically available, resulting in seizures, acidosis, and serious neurological damage. As the absence of hepatic biotinidase
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