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Key Documents

Y0001246

Azathioprine impurity G

European Pharmacopoeia (EP) Reference Standard

동의어(들):

6-[(1-Methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-7H-purin-2-amine

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About This Item

실험식(Hill 표기법):
C9H8N8O2S
CAS Number:
Molecular Weight:
292.28
UNSPSC 코드:
41116107
NACRES:
NA.24

Grade

pharmaceutical primary standard

API family

azathioprine

제조업체/상표

EDQM

응용 분야

pharmaceutical (small molecule)

형식

neat

InChI

1S/C9H8N8O2S/c1-16-3-13-6(17(18)19)8(16)20-7-4-5(12-2-11-4)14-9(10)15-7/h2-3H,1H3,(H3,10,11,12,14,15)

InChI key

YFTWHEBLORWGNI-UHFFFAOYSA-N

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일반 설명

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

Azathioprine impurity G EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

포장

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

기타 정보

Sales restrictions may apply.

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시험 성적서(COA)

Lot/Batch Number

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이 제품을 이미 가지고 계십니까?

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문서 라이브러리 방문

J Liliemark et al.
Therapeutic drug monitoring, 12(4), 339-343 (1990-07-01)
Two specific high-performance liquid chromatography methods for determining plasma concentrations of azathioprine and 6-mercaptopurine after oral administration of azathioprine are presented. It was shown that azathioprine is unstable in the blood samples unless immediately cooled in ice water. The 2-amino
T A Krenitsky et al.
Journal of medicinal chemistry, 32(7), 1471-1475 (1989-07-01)
Azathioprine [Imuran; 6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-1H-purine] is a widely used immunosuppressive and antiarthritic drug. For the sake of comparison, the riboside, the 2'-deoxyriboside, and the arabinoside of azathioprine and its 2-amino congener, thiamiprine, were prepared by an enzymatic method. In vitro, the cytotoxicities

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