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Merck
모든 사진(1)

주요 문서

SMB01333

Sigma-Aldrich

Acetyl-6-formylpterin

≥95% (HPLC)

동의어(들):

2-Acetamido-4-oxopteridine-6-carboxaldehyde, 2-Acetamido-6-formylpteridin-4(3H)-one, 2-Acetylamino-4-hydroxy-6-formylpteridine, 2-Acetamido-6-formylpteridin-4-one, N-(6-formyl-4-hydroxy-2-pteridinyl)acetamide, N-(6-formyl-4-oxo-1H-pteridin-2-yl)acetamide

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About This Item

실험식(Hill 표기법):
C9H7N5O3
CAS Number:
Molecular Weight:
233.18
MDL number:
UNSPSC 코드:
12352205
NACRES:
NA.77

Quality Level

분석

≥95% (HPLC)

양식

powder

저장 온도

−20°C

SMILES string

CC(=O)NC1=NC2=NC=C(N=C2C(=O)N1)C=O

InChI

1S/C9H7N5O3/c1-4(16)11-9-13-7-6(8(17)14-9)12-5(3-15)2-10-7/h2-3H,1H3,(H2,10,11,13,14,16,17)

InChI key

DDBCPKAHJKOGKK-UHFFFAOYSA-N

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일반 설명

Acetyl-6-formylpterin is a vitamin B9 (folate) metabolite and ligand to MHC class I-related protein 1 (MR1) antigens presented on mucosal-associated invariant T (MAIT) cells.
Acetyl-6-formylpterin, also known as 2-Acetamido-6-formylpteridin-4-one, is a pteridine derivative and a reductive amination product derived from folic acid. This unique compound undergoes a reductive amination reaction, generating formyl groups that can be subsequently acetylated or alkylated, resulting in the formation of stable compounds with diverse properties. Current research highlights the multifaceted nature of this compound, indicating its potential biological activities, including neuroprotective, antitumor, and anticancer properties.

Moreover, acetyl-6-formylpterin serves as a precursor in the synthesis of 2′-hydroxy-7,8-dihydrofolate, a metabolite associated with para-aminosalicylic acid (PAS) in M. tuberculosis. This compound′s versatility and involvement in various biological processes make it an intriguing molecule for metabolomics and biochemical research.

애플리케이션

Acetyl-6-formylpterin has been used:
  • to study the potential reversal of iver fibrosis
  • in metabolomics research

생화학적/생리학적 작용

Acetyl-6-formylpterin is involved in the enzymatic conversion of GTP to BH4, playing a role in the regulation of neurotransmitter synthesis and other biological processes.

특징 및 장점

  • Can be used in Metabolomics and Biochemical research
  • High-quality compound suitable for multiple research applications

기타 정보

For additional information on our range of Biochemicals, please complete this form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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