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Merck
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Key Documents

SMB00978

Sigma-Aldrich

L-Hercynine

≥95% (HPLC)

동의어(들):

α-N,N,N-Trimethylhistidine, N-α-trimethyl histidine, Histidine-betaine

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About This Item

실험식(Hill 표기법):
C9H15N3O2
CAS Number:
Molecular Weight:
197.23
NACRES:
NA.26

Quality Level

분석

≥95% (HPLC)

형태

solid

저장 온도

2-8°C

SMILES string

C[N+](C)(C)[C@H](C([O-])=O)CC1=CN=CN1

InChI

1S/C9H15N3O2/c1-12(2,3)8(9(13)14)4-7-5-10-6-11-7/h5-6,8H,4H2,1-3H3,(H-,10,11,13,14)/t8-/m0/s1

InChI key

GPPYTCRVKHULJH-QMMMGPOBSA-N

일반 설명

Hercynine is the precursor and redox metabolite of ergothioneine, which regulates microbial physiology and enables the survival of microbes under stressful conditions encountered in their natural environments. Ergothioneine is primarily present as a thione physiological pH, which makes it resistant to autoxidation. Ergothioneine enables pathogenic microbes, such as Mycobacterium tuberculosis (Mtb) to withstand hostile environments within the host to establish infection.

애플리케이션

Hercynine is a versatile molecule and it finds application in biochemical and metabolomics research.

특징 및 장점

  • Can be used in Metabolomics and Biochemical research
  • High-quality compound suitable for multiple research applications

기타 정보

For additional information on our range of Biochemicals, please complete this form.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

Salvatore Sotgia et al.
Antioxidants (Basel, Switzerland), 9(9) (2020-09-17)
The dependence of a stallion's spermatozoa on oxidative phosphorylation for energy requirements results in an unconventional relationship between reactive oxygen species (ROS) production and fertility. In such a scenario, antioxidant activity must be finely controlled and not affect the essential
Tomoyuki Kamide et al.
Journal of agricultural and food chemistry, 68(23), 6390-6394 (2020-05-22)
We previously constructed a heterologous production system for ergothioneine (ERG) in Escherichia coli using five ERG biosynthesis genes (egtABCDE) from Mycobacterium smegmatis. However, significant amounts of hercynine (HER), an intermediate of ERG, as ERG were accumulated, suggesting that the reaction

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