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Merck
모든 사진(1)

주요 문서

69732

Millipore

Lithium mupirocin Supplement

suitable for microbiology,

Selectively inhibits the growth of lactic acid bacteria

동의어(들):

Lithium mupirocin solution, Li-MUP, MUP supplement

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About This Item

실험식(Hill 표기법):
C26H43LiO9
CAS Number:
Molecular Weight:
506.56
MDL number:
UNSPSC 코드:
41171614
PubChem Substance ID:
NACRES:
NA.85

Agency

ISO 29981:2010

Quality Level

무균

sterile (Filtered and Aseptic Handled)
sterile

양식

liquid

유통기한

limited shelf life, expiry date on the label

응용 분야

environmental
food and beverages

microbiology

저장 온도

2-8°C

적합성

Lactobacillus spp.
Lactococcus spp.
Leuconostoc spp.
Streptococcus spp.

SMILES string

[Li+].C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@H]2CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)[C@H](O)[C@@H]2O

InChI

1S/C26H44O9.Li/c1-16(13-23(30)33-11-9-7-5-4-6-8-10-22(28)29)12-20-25(32)24(31)19(15-34-20)14-21-26(35-21)17(2)18(3)27;/h13,17-21,24-27,31-32H,4-12,14-15H2,1-3H3,(H,28,29);/q;+1/p-1/b16-13+;/t17-,18-,19-,20-,21-,24+,25-,26-;/m0./s1

InChI key

XFIKMPRBSORKQP-JATHGWPISA-M

일반 설명

Lithium mupirocin is isolated from Pseudomonas fluorescens. At lower concentrations, it has bacteriostatic characteristics, while at higher concentrations it is bacteriocidal. Mupirocin is active against gram-positive bacteria such as Methicillin-resistant Staphylococcus aureus (MRSA), Lactobacilli, Lactococci, Streptococci and Leuconostocs. Mupirocin has been used to study mupirocin resistance in Mycoplasma bacteria. Mupirocin inhibits the isoleucyl-tRNA synthetase, which finally results in inhibition of protein and RNA synthesis. Mupirocin lithium salt is freely soluble in water.

애플리케이션

Lithium mupirocin supplement is used for selective enumeration of Bifidobacteria from fermented milk products along with the TOS-propionate agar according to ISO 29981:2010 and IDF 220:2010

성분

Composition:
(5ml, sufficient for 100 ml medium)
Mupirocin 5 mg
sterile distilled water 5.0 ml

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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문서 라이브러리 방문

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Food Control, 34, 691-697 (2013)
J Gilbart et al.
Antimicrobial agents and chemotherapy, 37(1), 32-38 (1993-01-01)
Mupirocin resistance in Staphylococcus aureus results from changes in the target enzyme, isoleucyl-tRNA synthetase (IRS). Twelve strains of S. aureus comprising four susceptible (MICs < or = 4 micrograms/ml), four intermediate level-resistant (MICs between 8 and 256 micrograms/ml), and four
Krešimir Matanovic et al.
Journal of clinical microbiology, 51(3), 1005-1007 (2012-12-28)
The genetic analysis of high-level mupirocin resistance (Hi-Mup(r)) in a Staphylococcus pseudintermedius isolate from a dog is presented. The Hi-Mup(r) ileS2 gene flanked by a novel rearrangement of directly repeated insertion sequence IS257 elements was located, together with the aminoglycoside
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