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Merck
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Key Documents

32138

Supelco

Doripenem monohydrate

VETRANAL®, analytical standard

동의어(들):

(4R,5S,6S)-6-[(1R)-1-Hydroxyethyl]-4-methyl-7-oxo-3-[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

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About This Item

실험식(Hill 표기법):
C15H24N4O6S2 · H2O
CAS Number:
Molecular Weight:
438.52
Beilstein:
15340136
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

analytical standard

Quality Level

제품 라인

VETRANAL®

기술

HPLC: suitable
gas chromatography (GC): suitable

응용 분야

forensics and toxicology
veterinary

형식

neat

저장 온도

2-8°C

SMILES string

[H]O[H].NS(NC[C@H](C1)NC[C@H]1SC2=C(C(O)=O)N3C([C@]([H])([C@H](O)C)[C@@]3([H])[C@H]2C)=O)(=O)=O

InChI

1S/C15H24N4O6S2.H2O/c1-6-11-10(7(2)20)14(21)19(11)12(15(22)23)13(6)26-9-3-8(17-5-9)4-18-27(16,24)25;/h6-11,17-18,20H,3-5H2,1-2H3,(H,22,23)(H2,16,24,25);1H2/t6-,7-,8+,9+,10-,11-;/m1./s1

InChI key

NTUBEBXBDGKBTJ-WGLOMNHJSA-N

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일반 설명

Doripenem belongs to the carbapenems family of β-lactam antibiotic compounds.

애플리케이션

Doripenem monohydrate can be used as the precursor for the preparation of doripenem which may be used as an analytical reference standard for the determination of doripenem in:
  • Bovine muscle by liquid chromatography combined with tandem mass spectrometry (LC-MS/MS).
  • Bulk drug and formulations by high performance thin layer chromatography (HPTLC).
  • Medicinal products by capillary electrophoresis coupled to ultraviolet (UV) detector as well as micellar electrokinetic chromatography (MEKC) with UV detection.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

법적 정보

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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시험 성적서(COA)

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문서 라이브러리 방문

이미 열람한 고객

Determination of biapenem in a medicinal product by micellar electrokinetic chromatography with sweeping in an enhanced electric field.
Michalska K, et al.
Journal of Chromatography A, 1282(4), 153-160 (2013)
Determination of doripenem and related substances in medicinal product using capillary electrophoresis.
Michalska K, et al.
Journal of Separation Science, 34(4), 475-482 (2011)
A validated HPTLC method for the determination of doripenem in pharmaceutical dosage forms.
Kurien J, et al.
International Journal of Pharmaceutical Sciences Review and Research, 27, 317-321 (2014)
M Di Rocco et al.
Journal of chromatography. A, 1500, 121-135 (2017-04-30)
A method was developed for the confirmatory and quantitative analysis of 30 β-lactam antibiotic residues in bovine muscle. The method includes 12 penicillins (amoxicillin, ampicillin, cloxacillin, dicloxacillin, mecillinam, methicillin, nafcillin, oxacillin, penicillin G, penicillin V, piperacillin, ticarcillin), 12 cephalosporins (cefacetrile

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