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Merck
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Key Documents

15523-M

Sigma-Aldrich

Glycerol

puriss., meets analytical specification of Ph. Eur., BP, USP, FCC, E422, anhydrous, 99.0-101.0% (alkalimetric)

동의어(들):

1,2,3-Propanetriol, Glycerin

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About This Item

Linear Formula:
HOCH2CH(OH)CH2OH
CAS Number:
Molecular Weight:
92.09
Beilstein:
635685
EC Number:
MDL number:
UNSPSC 코드:
12352104
PubChem Substance ID:
NACRES:
NA.21

Agency

meets analytical specifications of BP
meets analytical specifications of E422
meets analytical specifications of Ph. Eur.
meets analytical specifications of USP

Quality Level

규정 준수

meets analytical specifications of FCC

vapor density

3.1 (vs air)

vapor pressure

<1 mmHg ( 20 °C)

grade

puriss.

분석

99.0-101.0% (alkalimetric)
99.0-101.0% (calc. on H2O free substance)

형태

liquid

autoignition temp.

698 °F

품질

meets analytical specification of Ph. Eur., BP, USP, FCC, E422

기술

IR spectroscopy: suitable
electrophoresis: suitable

불순물

acidity or alkalinity, complies
acrolein, glucose and NH4-compounds, complies
ester, complies
fatty acids and esters, complies
impurities A and related substances (GC), complies
residual solvents, complies
sugar, complies
≤0.003% free acid (as CH3COOH)
≤0.2% 1,2,4-butantriole (GC)
≤10 ppm aldehydes (as HCHO)
≤2% water (Karl Fischer)
≤30 ppm halogen compounds (as Cl)
≤5 ppm heavy metals (as Pb)

무기 잔류물

≤0.01% (as SO4)

refractive index

n20/D 1.471-1.474
n20/D 1.474 (lit.)

pH

5.5-8

bp

182 °C/20 mmHg (lit.)

mp

20 °C (lit.)

density

1.2580-1.2644 g/mL at 20 °C
≥1.257 g/mL at 25 °C
1.25 g/mL (lit.)

SMILES string

OCC(O)CO

음이온 미량물

chloride (Cl-): ≤10 ppm
sulfate (SO42-): ≤10 ppm

양이온 미량물

As: ≤1 ppm
Cu: ≤0.001%
Pb: ≤1 ppm
Zn: ≤0.001%

적합성

complies for appearance of solution
complies for reaction against H2SO4
corresponds for chromatography
passes test for identity (IR)

InChI

1S/C3H8O3/c4-1-3(6)2-5/h3-6H,1-2H2

InChI key

PEDCQBHIVMGVHV-UHFFFAOYSA-N

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일반 설명

Glycerol is odourless, colorless, viscous in nature, and exists as a sweet tasting liquid. It can be derived naturally as well as from petrochemical feedstock. Glycerol has a wide variety of applications, and is one of the most valuable and versatile chemical substances in nature. It can be used as an emollient, solvent, sweetening agent, in pharmaceutical formulations, cosmetics, foodstuffs and toiletries. It is very stable and can be easily stored under normal temperature; also it is non-irritating and has no adverse impact to the environment.

생화학적/생리학적 작용

Glycerol has been used as
  • a supplement during cell culture of Mycobacterium tuberculosis and Mycobacterium avium.
  • a fuel during designing enzymatic biofuel cell.
  • a liquid composite matrix with 4-HCCA and 3-amino­quinoline for analysis of neutral and acidic glycans.
  • a matrix for fast atom bombardment MS.
  • may be employed as liquid matrix for the quantification studies by MALDI (Matrix-assisted laser desorption/ionization mass spectrometry) analysis.
Glycerol is hygroscopic in nature and is soluble in water owing to its three hydrophilic alcoholic hydroxyl groups. It can form both inter- and intramolecular hydrogen bonds, making it a very flexible molecule. The physiologic effect of glycerine is due to cell-mediated immunity, increased IgG production and increased histamine release.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point (°F)

320.0 °F - closed cup

Flash Point (°C)

160 °C - closed cup


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