MHSTCMAG-70K

MILLIPLEX^® Mouse High Sensitivity T Cell Panel - Immunology Multiplex Assay

Simultaneous analyze low levels of cytokine and chemokine biomarker with the High Sensitivity Bead-Based Multiplex Assays using the Luminex technology, in mouse serum, plasma and cell culture samples.

• 동의어(들): Luminex^® Mouse Immunology Panel, Millipore Mouse Immunology Panel, Mouse Immunology Protein Multiplex Assay
• UNSPSC 코드: 12161503
• eCl@ss: 32161000
• NACRES: NA.47

속성

• Quality Level: 200
• 종 반응성: mouse
• 제조업체/상표: Milliplex^®
• assay range: accuracy: 82-102%; sensitivity: 0.26-11.14 pg/mL; standard curve range: 0.10-400 pg/mL; (IL-4); standard curve range: 0.49-2,000 pg/mL; (IFNγ); standard curve range: 0.49-2,000 pg/mL; (IL-17A); standard curve range: 0.49-2,000 pg/mL; (IL-7); standard curve range: 0.49-2,000 pg/mL; (TNFα); standard curve range: 0.73-3,000 pg/mL; (KC/GROα/CXCL1); standard curve range: 0.98-4,000 pg/mL; (IL-2); standard curve range: 0.98-4,000 pg/mL; (IL-5); standard curve range: 0.98-4,000 pg/mL; (IL-6); standard curve range: 1.34-5,500 pg/mL; (IL-10); standard curve range: 2.93-12,000 pg/mL; (IL-12 (p70)); standard curve range: 3.17-13,000 pg/mL; (LIX); standard curve range: 3.42-14.000 pg/mL; (IL-13); standard curve range: 3.91-16,000 pg/mL; (IL-1α); standard curve range: 3.91-16,000 pg/mL; (IL-1β); standard curve range: 3.91-16,000 pg/mL; (MCP-1/CCL2); standard curve range: 6.1-25,000 pg/mL; (GM-CSF); standard curve range: 7.32-30,000 pg/mL; (MIP-2/CXCL2); inter-assay cv: <15%; intra-assay cv: <10%
• 기술: multiplexing: suitable
• 검출 방법: fluorometric (Luminex xMAP)
• 배송 상태: ambient

설명

일반 설명

Cytokines are immunomodulatory polypeptides that play key roles in both adaptive and innate immune responses. A generic term, “cytokines” includes myokines (produced by muscle cells), lymphokines (produced by activated Th cells), interleukins (acting as mediators between T cells), and chemokines (responsible for T-cell migration). One of the regulatory mechanisms of the immune system, cytokines act at the recognition, activation, or effector phases of an immune response, modulating the development and functional activities of the subtypes of T cells, B cells, and myeloid cells. Research involving cytokines plays a significant role in achieving a deeper understanding of the immune system and its multi-faceted response to most antigens, especially those responses that make up the inflammatory process.

Low levels of inflammation are involved in many clinical and sub-clinical disease states, such as autoimmune disease, cardiovascular disease, diabetes, neurological disorders, and cancer. Measuring picogram levels of cytokines, therefore, is critical for understanding the pathogenesis of these diseases.

Panel Type: Cytokines/Chemokines

특이성

Cross Reactivty
There is no detectable cross-reactivity within the panel.

Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.

애플리케이션

• Analytes: GM-CSF, IFNγ, IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-7, IL-10, IL-12 (p70), IL-13, IL-17A, KC/CXCL1, LIX, MCP-1, MIP-2, TNF-α
• Recommended Sample type: serum, plasma, tissue culture or other media
• Recommended Sample dilution: neat or 1:2 diluted serum or plasma
• Assay Run Time: Overnight
• Research Category: Inflammation & Immunology
• Research Subcategory: Immune Response Metabolic Disorders Chronic Inflammatory Disease Cardiovascular Disease

특징 및 장점

Design your multiplex kit by choosing available analytes within this panel.

저장 및 안정성

Recommended storage for kit components is 2 - 8°C.

기타 정보

Please contact Technical Service for linearity of dilution.

Sensitivity: Please see protocol for sensitivity of individual analytes.

법적 정보

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• 픽토그램: GHS08,GHS05,GHS07,GHS09
• 신호어: Danger
• 유해 및 위험 성명서: H302 + H312 + H332,H317,H318,H373,H411
• 예방조치 성명서: P273 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
• 표적 기관: Respiratory Tract
• Storage Class Code: 10 - Combustible liquids