추천 제품
material
flat bottom wells
polycarbonate membrane
polystyrene
Quality Level
설명
Clear, Sterile, 5.0 µm pore size, Polycarbonate (PC) membrane, 10 plates
무균
sterile
제품 라인
MultiScreen®
특징
lid
제조업체/상표
MultiScreen®
파라미터
50-250 μL sample volume (per well)
기술
DNA purification: suitable
여과 면적
0.28 cm2
플레이트 크기
96 wells
웰 최대 용적
350 μL
작업 용적
50-75 μL
공극 크기
5.0 μm pore size
결합 유형
Tissue Culture (TC)-treated surface
배송 상태
ambient
관련 카테고리
일반 설명
The MultiScreen®-MIC (Migration, Invasion, Chemotaxis) plate is a 96-well disposable device for use in functional assays for screening protein libraries and compound leads for drug discovery. It is designed to support high throughput cell-based functional assays such as migration, invasion, and chemotaxis with suspension and/or adherent cell lines, using a single device. The plates can be used to perform and quantify cell migration or invasion across coated or uncoated membranes in response to a concentration gradient. The MultiScreen-MIC plates are available in several pore sizes to accommodate MIC assays with a variety of cell lines and are intended for single use only.
애플리케이션
MultiScreen® Migration Invasion and Chemotaxis Filter Plate, 96 well has been used in the transwell/cellular migration assay using:
- interleukin (IL)-4- and IL-12-treated T cells
- THP-1 (human acute monocytic leukemia cell line)
- in vitro activated, purified and IL-2-maintained galectin-3-deficient (gal3)-/- and gal3+/+ cluster of differentiation 4 (CD4)+ OTII T cells
법적 정보
MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany
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시험 성적서(COA)
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Proceedings of the National Academy of Sciences of the United States of America, 106(34), 14496-14501 (2009-08-27)
We have investigated the function of endogenous galectin-3 in T cells. Galectin-3-deficient (gal3(-/-)) CD4(+) T cells secreted more IFN-gamma and IL-4 than gal3(+/+)CD4(+) T cells after T-cell receptor (TCR) engagement. Galectin-3 was recruited to the cytoplasmic side of the immunological
Journal of medicinal chemistry, 58(12), 5028-5037 (2015-06-04)
The Rho kinases (ROCK1 and ROCK2) are highly homologous serine/threonine kinases that act on substrates associated with cellular motility, morphology, and contraction and are of therapeutic interest in diseases associated with cellular migration and contraction, such as hypertension, glaucoma, and
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