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Merck
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Key Documents

MAMIC5S10

Millipore

Multiscreen® 96 well Plate, polycarbonate membrane

pore size 5.0 μm, sterile

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About This Item

UNSPSC 코드:
41104923
eCl@ss:
32039006
NACRES:
NB.22

material

flat bottom wells
polycarbonate membrane
polystyrene

Quality Level

설명

Clear, Sterile, 5.0 µm pore size, Polycarbonate (PC) membrane, 10 plates

무균

sterile

제품 라인

MultiScreen®

특징

lid

제조업체/상표

MultiScreen®

파라미터

50-250 μL sample volume (per well)

기술

DNA purification: suitable

여과 면적

0.28 cm2

플레이트 크기

96 wells

웰 최대 용적

350 μL

작업 용적

50-75 μL

공극 크기

5.0 μm pore size

결합 유형

Tissue Culture (TC)-treated surface

배송 상태

ambient

관련 카테고리

일반 설명

The MultiScreen®-MIC (Migration, Invasion, Chemotaxis) plate is a 96-well disposable device for use in functional assays for screening protein libraries and compound leads for drug discovery. It is designed to support high throughput cell-based functional assays such as migration, invasion, and chemotaxis with suspension and/or adherent cell lines, using a single device. The plates can be used to perform and quantify cell migration or invasion across coated or uncoated membranes in response to a concentration gradient. The MultiScreen-MIC plates are available in several pore sizes to accommodate MIC assays with a variety of cell lines and are intended for single use only.

애플리케이션

MultiScreen® Migration Invasion and Chemotaxis Filter Plate, 96 well has been used in the transwell/cellular migration assay using:
  • interleukin (IL)-4- and IL-12-treated T cells
  • THP-1 (human acute monocytic leukemia cell line)
  • in vitro activated, purified and IL-2-maintained galectin-3-deficient (gal3)-/- and gal3+/+ cluster of differentiation 4 (CD4)+ OTII T cells

법적 정보

MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany

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문서 라이브러리 방문

Huan-Yuan Chen et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(34), 14496-14501 (2009-08-27)
We have investigated the function of endogenous galectin-3 in T cells. Galectin-3-deficient (gal3(-/-)) CD4(+) T cells secreted more IFN-gamma and IL-4 than gal3(+/+)CD4(+) T cells after T-cell receptor (TCR) engagement. Galectin-3 was recruited to the cytoplasmic side of the immunological
Jeremy Green et al.
Journal of medicinal chemistry, 58(12), 5028-5037 (2015-06-04)
The Rho kinases (ROCK1 and ROCK2) are highly homologous serine/threonine kinases that act on substrates associated with cellular motility, morphology, and contraction and are of therapeutic interest in diseases associated with cellular migration and contraction, such as hypertension, glaucoma, and

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