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Merck
모든 사진(1)

Key Documents

MABT42

Sigma-Aldrich

Anti-Integrin beta-2 (CD18) Antibody, clone M18/2

clone M18/2, from rat

동의어(들):

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), integrin beta chain, beta 2, complement receptor C3 beta-subunit, leukocyte cell adhesion molecule CD18, integrin beta-2, Complement receptor C3 subunit beta, Cell surface adhesion glyco

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rat

Quality Level

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

M18/2, monoclonal

종 반응성

mouse

기술

flow cytometry: suitable
immunoprecipitation (IP): suitable

동형

IgG2aκ

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

mouse ... Itgb2(16414)

일반 설명

Integrin beta-2, also known as CD18, is an adhesion receptor in neutrophils that interacts with cytohesin-1 intracellularly. Integrin beta is instrumental in activation-dependent adhesion and adhesion-dependent signaling. Expression of integrin beta-2 has a positive correlation with patient survival from malignant B cell lymphoma.

면역원

Whole B10 mouse spleen cells enriched with T-cells.

애플리케이션

Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP (Sanchez-Madrid, F., et al. (1983). J. ExP. MED. 158:586-602).

Inhibition Analysis: A previous lot of this antibody was shown to inhibit lymphoma metastasis (Zahalka, M. A. et al. (1993) J. Immunol. 150, 4466).
This Anti-Integrin beta-2 (CD18) Antibody, clone M18/2 is validated for use in FC, IP for the detection of Integrin beta-2 (CD18).

품질

Evaluated by Flow Cytometry in mouse EL4 cells.

Flow Cytometry Analysis: 10 µg of this antibody detected Integrin beta-2 in mouse EL4 cells.

표적 설명

85 kDa calculated

물리적 형태

Format: Purified

분석 메모

Control
Mouse EL4 cells

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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