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Merck
모든 사진(1)

Key Documents

MABF458

Sigma-Aldrich

Anti-CD86 (B7-2) Antibody (mouse), PE, clone GL-1

clone GL-1 (GL1), 0.2 mg/mL, from rat

동의어(들):

T-lymphocyte activation antigen CD86, Activation B7-2 antigen, Early T-cell costimulatory molecule 1, ETC-1, CD86

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rat

Quality Level

결합

PE

항체 형태

purified antibody

항체 생산 유형

primary antibodies

클론

GL-1 (GL1), monoclonal

종 반응성

mouse

농도

0.2 mg/mL

기술

flow cytometry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable

동형

IgG2aκ

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

mouse ... Cd86(12524)

관련 카테고리

일반 설명

The GL-1 antibody reacts with mouse CD86, also known as B7-2, an 80 kDa cell surface protein which is a ligand for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 can also bind a second B7 ligand known as CD80 (B7-1). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. The GL-1 antibody may be used as a marker for CD86 expression on B cells, macrophages, and dendritic cells.

면역원

Immunogen information for this antibody is proprietary information.

애플리케이션

Research Category
Inflammation & Immunology
This rat monoclonal antibody Anti-CD86 (B7-2) (mouse), PE, clone GL-1 validated for use in IHC, Immunofluorescence & Flow Cytometry for the detection of CD86 (B7-2).

품질

The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.125 µg of this antibody detected CD86 (B7-2) in one million C57Bl/6 splenocytes.

물리적 형태

Purified Rat Monoclonal Antibody in buffer containing 10 mM NaH2PO4, 150 mM NaCl, 0.1% gelatin, pH 7.2, and up to 0.1% sodium azide.
Size Exclusion Chromatography

저장 및 안정성

It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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