MABF271

Anti-FPR1/2 Antibody, clone NFPR1

clone NFPR1, from mouse

• 동의어(들): Anti-Formyl Peptide Receptor 1/2, FMLP1/2, fMet-Leu-Phe receptor, fMLP receptor, N-formyl peptide receptor, FPR, N-formylpeptide chemoattractant receptor
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: NFPR1, monoclonal
• 종 반응성: human
• 기술: flow cytometry: suitable; immunocytochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• 동형: IgG1κ
• NCBI 수납 번호: NP_001180235
• UniProt 수납 번호: P21462
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... FPR1(2357)

설명

일반 설명

N-formy peptide receptor 1 (also known as N-formylpeptide chemoattractant receptor or fMet-Leu-Phe receptor) & 2 (also known as RFP, FMLP-R-I, Lipoxin A4 receptor, LXA4 receptor, FMLP-related receptor I, Formyl peptide receptor-like 1) are multi-pass cell membrane G protein-coupled receptors (GPCRs) encoded by the FPR1 (also known as FPR and FMLP) and FPR2 (also known as FPR2 and FMLP-R-II) gene in human, respectively. The FPR1 gene encodes the high-affinity, and FPR2 the low-affinity, receptor for N-formyl-methionyl peptides (FMLP). Both receptors mediate FMLP-induced activation of neutrophils.

특이성

This antibody is epitope mapped, recognizing cytoplasmic c-terminal tail residues of FPR1 (305-GQDFRERLI-313) and of FPR2 (306- GQDFRERLI-314) (Riesselman, M., et al. (2007). J. Immunol. 179:2520-2531).

면역원

Epitope: FPR1 (305-GQDFRERLI-313) and FPR2 (306- GQDFRERLI-314)

His-tagged recombinant protein corresponding to the FPR1 (305-GQDFRERLI-313) and FPR2 (306- GQDFRERLI-314) of human FPR1/2.

애플리케이션

Anti-FPR1/2 Antibody, clone NFPR1 is an antibody against FPR1/2 for use in Western Blotting, Flow Cytometry, Immunocytochemistry, Immunoprecipitation.

Flow Cytometry Analysis: A representative lot detected FPR1/2 in human neutraphils (Riesselman, M., et al. (2007). J. Immunol. 179:2520-2531).
Immunocytochemistry Analysis: A representative lot detected FPR1/2 in human neutraphils (Riesselman, M., et al. (2007). J. Immunol. 179:2520-2531).
Immunoprecipitation Analysis: A representative lot immunoprecipitated FPR1/2 in neutraphils (Maaty, W.S., et al. (2013). JBC. 288(38):27042-27058).
Western Blotting Analysis: A representative lot detected FPR1/2 in neutraphils (Maaty, W.S., et al. (2013). JBC. 288(38):27042-27058).

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

품질

Evaluated by Western Blotting in THP-1 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected FPR1/2 in 10 µg of THP-1 cell lysate.

표적 설명

~38 kDa observed. Uncharacterized band(s) may appear in some lysates.

물리적 형태

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

기타 정보

Concentration: Please refer to lot specific datasheet.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1