MABF240

Anti-hGITR Antibody, clone 108-17

clone 108-17, from mouse

• 동의어(들): Tumor necrosis factor receptor superfamily member 18, Activation-inducible TNFR family receptor, Glucocorticoid-induced TNFR-related protein, CD357
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 108-17, monoclonal
• 종 반응성: mouse, human, rat
• 기술: western blot: suitable
• 동형: IgG1κ
• NCBI 수납 번호: NP_004186
• UniProt 수납 번호: Q9Y5U5
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... TNFRSF18(8784)

설명

일반 설명

Glucocorticoid-induced TNFR-related protein (hGITR) is also called Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), Activation-inducible TNFR family receptor (AITR) and CD357. hGITR is a receptor for TNFSF18 and is activated by NF-kappa-B through the TRAF2/NIK pathway. hGITR is thought to be involved in activated T-lymphocyte and endothelial cell interactions, as well as regulation of T-cell receptor-mediated cell death. hGITR is expressed in lymph node, peripheral blood leukocytes and at low levels in the spleen.

면역원

Recombinant protein corresponding to human hGITR.

애플리케이션

Anti-hGITR Antibody, clone 108-17 is a highly specific mouse monoclonal antibody & that targets GITR & has been tested in western blotting.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Western Blotting Analysis: 1.0 µg/mL from a representative lot detected hGITR in 10 µg of mouse lymph node, rat spleen, and rat thymus tissue lysate.

품질

Evaluated by Western Blotting in human spleen tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected hGITR in 10 µg of human spleen tissue lysate.

표적 설명

~ 26 kDa observed. Multiple bands can be observed due to GITR being a monomer & homeodimer in some lysates. Uncharacterized band(s) may appear in some lysates.

물리적 형태

Format: Purified

Protein A purified

Purified mouse monoclonal IgG1κ in buffer containing PBS with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable