MABC532

Anti-PTHrP Antibody, clone 4C4.1

clone 4C4.1, from mouse

• 동의어(들): Parathyroid hormone-related protein, PTHrP, PTH-rP, Parathyroid hormone-like protein, PLP
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 4C4.1, monoclonal
• 종 반응성: human
• 기술: western blot: suitable
• 동형: IgG1κ
• NCBI 수납 번호: NP_945316
• UniProt 수납 번호: P12272
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... PTHLH(5744)

설명

일반 설명

Parathyroid hormone-related protein (UniProt P12272; also known as Parathyroid hormone-like related protein, Parathyroid hormone-like hormone preproprotein, PLP, PTH-related protein, PTH-rP, PTHrP) is encoded by the PTHLH (also known as BDE2, HHM, PTHR, PTHRP) gene (Entrez Gene ID 5744) in human. Parathyroid hormone-related protein is initially translated as a 177 amino acid preproprotein with an N-terminal signal sequence (aa 1-24) and a propeptide sequence (aa 25-34), which are later removed to yield the mature protein. The mature protein is further cleaved to produce PTHrP[1-34] (aa 37-70), PTHrP[1-36] (aa 37-72), PTHrP[38-94] (aa 74-130), and PTHrP[107-139] (aa 143-175; also known as Osteostatin). PTHrP is produced in a wide variety of tissues, where it acts as a paracrine or autocrine factor to regulate cellular and organ growth, development, migration, differentiation, calcium transport, survival and apoptosis.

면역원

GST-tagged recombinant human PTHrP lacking signal and propeptide sequence.

애플리케이션

Detect PTHLH using this mouse monoclonal Anti-PTHrP Antibody, clone 4C4.1, Cat. No. MABC532, validated for use in Western Blotting.

품질

Evaluated by Western Blotting in MCF-7 cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected PTHrP in 10 µg of MCF-7 cell lysate.

표적 설명

~16/6 kDa observed. Uncharacterized band(s) may appear in some lysates.

물리적 형태

Format: Purified

기타 정보

Concentration: Please refer to lot specific datasheet.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable