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Merck
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Key Documents

MAB8703

Sigma-Aldrich

Anti-Dengue Virus Type III Antibody, clone 5D4-11

clone 5D4-11, Chemicon®, from mouse

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

purified antibody

클론

5D4-11, monoclonal

종 반응성

human

제조업체/상표

Chemicon®

기술

immunofluorescence: suitable

동형

IgG1

배송 상태

wet ice

일반 설명

Dengue fever is an acute, mosquito-transmitted viral disease characterized by fever, headache, arthralgia (severe retro-orbital pain), myalgia, rash, nausea, and vomiting. Infections are caused by any of the four closely related, but antigenically distinct virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4). Infection with one of these serotypes does not provide cross-protective immunity, so persons living in a dengue-endemic area can have four dengue infections during their lifetimes. Dengue is primarily an urban disease of the tropics, and the viruses that cause it are maintained in a cycle that involves humans and Aedes aegypti, a domestic, day-biting mosquito that prefers to feed on humans. Although most dengue infections result in relatively mild illness, some can produce Dengue Hemorrhagic Fever (DHF) or dengue shock syndrome, with children being particularly at risk. Although epidemic outbreaks have been reported since 1779, the incidence has been increasing, with global, multiple serotype pandemics intensifying within the last 15 years. There is no specific antiviral therapy for dengue, but for both classical dengue and dengue hemorrhagic fever, symptomatic and supportive measures are effective. Important risk factors for DHF include the strain and serotype of the virus involved, as well as the age, immune status, and genetic predisposition of the patient.

특이성

Reacts with the Dengue type 3 virus.

면역원

Dengue virus antigens (H87).

애플리케이션

Anti-Dengue Virus Type III Antibody, clone 5D4-11 is an antibody against Dengue Virus Type III for use in IF.
Immunofluorescent assay.

Final working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral

물리적 형태

Format: Purified
Purified. 0.02M Phosphate Buffer, pH 7.6, 0.25M NaCl and 0.1% sodium azide.

저장 및 안정성

Maintain at 2-8°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리에서 최근에 구매한 제품에 대한 문서를 찾아보세요.

문서 라이브러리 방문

Evaluation by flow cytometry of antibody-dependent enhancement (ADE) of dengue infection by sera from Thai children immunized with a live-attenuated tetravalent dengue vaccine.
Bruno Guy, Pornthep Chanthavanich, Sophie Gimenez, Chukiat Sirivichayakul et al.
Vaccine null
Identification of distinct antigenic determinants on dengue-2 virus using monoclonal antibodies.
Gentry, M K, et al.
The American Journal of Tropical Medicine and Hygiene, 31, 548-555 (1982)
Dengue virus-specific and flavivirus group determinants identified with monoclonal antibodies by indirect immunofluorescence
Henchal, E A, et al
The American Journal of Tropical Medicine and Hygiene, 31, 830-836 (1982)

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