MAB5416
Anti-Glutamate Receptor 3 Antibody, clone 3B3
clone 3B3, Chemicon®, from mouse
동의어(들):
AMPA-selective glutamate receptor 3, Glutamate receptor ionotropic, AMPA 3, glutamate receptor 3, glutamate receptor C, glutamate receptor subunit 3, glutamate receptor, ionotrophic, AMPA 3
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모든 사진(1)
About This Item
UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41
추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
purified antibody
항체 생산 유형
primary antibodies
클론
3B3, monoclonal
종 반응성
monkey, mouse, human
종 반응성(상동성에 의해 예측)
rat
제조업체/상표
Chemicon®
기술
immunocytochemistry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable
동형
IgG1κ
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... GRIA3(2892)
일반 설명
AMPA receptors mediate fast synaptic current at most excitatory synapses, with stoichiometry characterized by subtype composition.There are four types of AMPA selective GluR subunits (GluR1, GluR2, GluR3 and GluR4). Tetrameric or pentameric combinations of different subunits contributes to the functional diversity of AMPA receptors. The insertion or removal of GluR1/GluR4 oligomeric channels from postsynaptic membranes appears to be LTP/LTD activity dependent while GluR2/GluR3 oligomers are continuously cycling. Millipore’s anti-GluR2/3 antibody is useful for localizing expression of GluR2/GluR3 receptor assemblies in the PSD.
특이성
Reacts with Glutamate Receptor 3 (GluR3). No cross reactivity with GluR2.
면역원
Fusion protein, N-terminus of GluR3
애플리케이션
Anti-Glutamate Receptor 3 Antibody, clone 3B3 is an antibody against Glutamate Receptor 3 for use in WB, IC, IH, IH(P).
Immunohistochemistry: A previous lot of this antibody was used in IH.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
품질
Western Blot Analysis: A previous lot of this antibody was used in WB.
표적 설명
~ 110 kDa
물리적 형태
Format: Purified
Liquid in PBS. Contains no preservative.
분석 메모
Control
Brain
Hippocampal tissue
Brain
Hippocampal tissue
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Presynaptic localization of an AMPA-type glutamate receptor in corticostriatal and thalamostriatal axon terminals.
Fumino Fujiyama, Eriko Kuramoto, Keiko Okamoto, Hiroyuki Hioki, Takahiro Furuta et al.
The European Journal of Neuroscience null
Glutamate receptor subunit 3 (GluR3) immunoreactivity delineates a subpopulation of parvalbumin-containing interneurons in the rat hippocampus.
Moga, Diana E, et al.
The Journal of Comparative Neurology, 462, 15-28 (2003)
Dopamine alters AMPA receptor synaptic expression and subunit composition in dopamine neurons of the ventral tegmental area cultured with prefrontal cortex neurons.
Gao, C; Wolf, ME
The Journal of Neuroscience null
Janusz Tucholski et al.
Schizophrenia research, 146(1-3), 177-183 (2013-03-07)
Numerous studies have demonstrated brain region- and subunit-specific abnormalities in the expression of subunits of the AMPA subtype of glutamate receptors in schizophrenia. In addition, abnormalities in the expression of proteins that regulate the forward trafficking of AMPA receptors through
Evolutionarily conserved pattern of AMPA receptor subunit glycosylation in Mammalian frontal cortex.
Tucholski, J; Pinner, AL; Simmons, MS; Meador-Woodruff, JH
Testing null
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