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Merck
모든 사진(2)

문서

MAB4350

Sigma-Aldrich

Anti-BMP-7 Antibody, clone 2A10

clone 2A10, from mouse

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

purified antibody

항체 생산 유형

primary antibodies

클론

2A10, monoclonal

종 반응성

mouse, human

기술

immunohistochemistry: suitable
western blot: suitable

입력

sample type mesenchymal stem cell(s)

동형

IgG1κ

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... BMP7(655)
mouse ... Bmp7(12162)

일반 설명

Bone morphogenetic protein-7 (BMP-7), also known as osteogenic protein-1, is a member of the TGF- superfamily, and is widely expressed during embryonic development. Like other members of the bone morphogenetic protein family, BMP-7 works synergistically with BMP-2 to play a key role in the differentiation of mesenchymal cells into bone and cartilage tissues by actively recruiting stem cells from the surrounding tissue, thereby initiating the bone formation cascade. In adult cells, BMP-7 is predominately expressed in the brain, kidneys, and bladder.

특이성

Reactivity with other species has not been tested.

애플리케이션

Immunohistochemistry: Recommended working dilution is 1:50.

Western Blotting: Recommended working concentration is 1 – 2 µg/mL.
This Anti-BMP-7 Antibody, clone 2A10 is validated for use in WB, IH for the detection of BMP-7.

표적 설명

46 kDa

물리적 형태

Format: Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4),
150 mM NaCl, and 0.05% sodium azide.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Three-dimensional epithelial and mesenchymal cell co-cultures form early tooth epithelium invagination-like structures: expression patterns of relevant molecules.
Li Xiao,Takeki Tsutsui
Journal of Cellular Biochemistry null
Oral administration of recombinant adeno-associated virus-mediated bone morphogenetic protein-7 suppresses CCl(4)-induced hepatic fibrosis in mice.
Hao, ZM; Cai, M; Lv, YF; Huang, YH; Li, HH
Molecular Therapy null
Ariadne Cristiane Cabral Cruz et al.
Journal of applied oral science : revista FOB, 20(6), 628-635 (2013-01-19)
Bone morphogenetic protein type 2 (BMP-2) is a potent local factor, which promotes bone formation and has been used as an osteogenic supplement for mesenchymal stem cells. This study evaluated the effect of a recombinant BMP-2 as well as the

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