생물학적 소스
mouse
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
6C1.3, monoclonal
종 반응성
human
제조업체/상표
Chemicon®
기술
western blot: suitable
입력
sample type neural stem cell(s)
동형
IgG2κ
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... MELK(9833)
일반 설명
Melk, (Maternal Embryonic Leucine Zipper Kinase) is a serine-threonine kinase of the snfI/AMPK family that is expressed in developing neuroepithelium, self-renewing neural stem cells and granule cell precursors. It is also considered an important brain tumor marker, being highly expressed in gliobastoma, astrocytomas, and medulablastomas.
면역원
MELK Recombinant protein.
애플리케이션
Research Category
Stem Cell Research
Stem Cell Research
Research Sub Category
Neural Stem Cells
Neural Stem Cells
This Anti-MELK Antibody, clone 6C1.3 is validated for use in WB for the detection of MELK.
Western blot: Recommended dilution: 1:500 (2 μg/mL)
Expected Molecular Weight: 74.5 kDa
Note: Bands may be present at a higher molecular weight due to glycosolation.
Expected Molecular Weight: 74.5 kDa
Note: Bands may be present at a higher molecular weight due to glycosolation.
표적 설명
74.5 kDA; glycosylations may result in higher MW bands in western blot.
물리적 형태
Format: Purified
Purified immunoglobulin in PBS, pH 7.0. Contains 0.1% sodium azide.
저장 및 안정성
1 year at 2-8 °C from date of shipment
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Lieve Verlinden et al.
The Journal of biological chemistry, 280(45), 37319-37330 (2005-09-08)
1,25-Dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) has potent antiproliferative effects characterized by a hampered G(1)/S transition. cDNA microarrays were used to monitor expression of 21,492 genes in MC3T3-E1 mouse osteoblasts at 1, 6, 12, 24, and 36 h after treatment with 1,25(OH)(2)D(3). Statistical
Mathew C Easterday et al.
Developmental biology, 264(2), 309-322 (2003-12-04)
The identification of the genes regulating neural progenitor cell (NPC) functions is of great importance to developmental neuroscience and neural repair. Previously, we combined genetic subtraction and microarray analysis to identify genes enriched in neural progenitor cultures. Here, we apply
Ichiro Nakano et al.
The Journal of cell biology, 170(3), 413-427 (2005-08-03)
Maternal embryonic leucine zipper kinase (MELK) was previously identified in a screen for genes enriched in neural progenitors. Here, we demonstrate expression of MELK by progenitors in developing and adult brain and that MELK serves as a marker for self-renewing
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