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Merck
모든 사진(1)

문서

MAB342

Sigma-Aldrich

Anti-Galactocerebroside Antibody, clone mGalC

clone mGalC, Chemicon®, from mouse

동의어(들):

Galactoceramide, Galactocerebroside, Galactosylceramide, GalC

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

mouse

Quality Level

항체 형태

purified antibody

클론

mGalC, monoclonal

종 반응성

mouse, human, rabbit, bovine, chicken, rat

제조업체/상표

Chemicon®

기술

ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable

동형

IgG3

배송 상태

dry ice

타겟 번역 후 변형

unmodified

일반 설명

Galactocerebroside (GalC) is a major galactosphingolipid of myelin which plays a role in myelination. GalC is a very useful, specific marker for oligodendroglial lineage.

특이성

Galactocerebroside (GalC), sulfatide, psychosine and other galactolipids. Cross-reacts with the sulfatide ester of GalC, but to a 16-fold lesser extent. No cross-reactivity with sphingosine, ceramide, mixed ganglioside or glucocerebroside. Binds specifically with oligodendrocytes and Schwann cells.

면역원

Synaptic plasma membranes from bovine hippocampus. Ranscht, B. et al. PNAS 79(8):2709-2713 (1982)

애플리케이션

Anti-Galactocerebroside Antibody, clone mGalC is an antibody against Galactocerebroside for use in ELISA, IC, & IHC.
Immunohistochemistry:
0.5-10 μg/mL of a previous lot was used on formalin fixed frozen sections of a prevous lot. Can not be used on paraffin embedded tissue sections since the antigen is denatured during embedding and paraffin removal.

Immunocytochemistry:
0.5-10 μg/mL of a previous lot was used on 4% paraformaldehyde, acetic acid or ethanol fixed cultured cells.

ELISA:
A previous lot was used on purified galactocerebrosides.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

물리적 형태

Format: Purified
Protein A purified
Purified mouse monoclonal in buffer containing 10 mM Potassium Phosphate, 150 mM NaCl, pH 7.4 containing 0.09% sodium azide.

저장 및 안정성

Stable for 1 year at -20ºC from date of receipt.

분석 메모

Control
Neonatal cortex

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Oligodendrocyte dysfunction after induction of experimental anterior optic nerve ischemia.
Goldenberg-Cohen, N; Guo, Y; Margolis, F; Cohen, Y; Miller, NR; Bernstein, SL
Investigative Ophthalmology & Visual Science null
T Matsushita et al.
Neuroscience, 136(1), 115-121 (2005-09-27)
The successive stages of development from oligodendrocyte progenitor to mature oligodendrocyte have been investigated in detail by using stage-specific antibodies. However, no cell lines are available that show stepwise differentiation from oligodendrocyte progenitors to mature oligodendrocytes. Here we show the
Cellular phenotype of androgen receptor-immunoreactive nuclei in the developing and adult rat brain.
Betty Lorenz, Luis Miguel Garcia-Segura, Lydia L DonCarlos
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Blockade of attachment and fusion receptors inhibits HIV-1 infection of human cervical tissue.
Hu, Q; Frank, I; Williams, V; Santos, JJ; Watts, P; Griffin, GE; Moore, JP; Pope, M; Shattock, RJ
The Journal of Experimental Medicine null
Valentina Caldera et al.
Journal of oncology, 2011, 314962-314962 (2011-08-27)
Formation of neurospheres (NS) in cultures of glioblastomas (GBMs), with self-renewal, clonogenic capacities, and tumorigenicity following transplantation into immunodeficient mice, may denounce the existence of brain tumor stem cells (BTSCs) in vivo. In sixteen cell lines from resected primary glioblastomas

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