추천 제품
제품명
Anti-Huntingtin Protein Antibody, a.a. 1247-1646, clone HU-4E6, ascites fluid, clone HU-4E6, Chemicon®
생물학적 소스
mouse
Quality Level
항체 형태
ascites fluid
항체 생산 유형
primary antibodies
클론
HU-4E6, monoclonal
종 반응성
mouse, human
제조업체/상표
Chemicon®
기술
ELISA: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable (paraffin)
immunoprecipitation (IP): suitable
western blot: suitable
동형
IgG2b
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... HTT(3064) , SLC6A4(6532)
특이성
Huntingtin Protein. No detectable cross reactivity with other proteins by Western blot.
면역원
Epitope: a.a. 1247-1646
Huntingtin fragment from aa 1247 to 1646 as a fusion protein
애플리케이션
Detect Huntingtin Protein using this Anti-Huntingtin Protein Antibody, a.a. 1247-1646, clone HU-4E6 validated for use in ELISA, IP, WB, IC, IH(P).
ELISA: 1:500-1:5,000
Western blot (recombinant protein, not suitable for the natural Huntingtin) : 1:500-1:5,000
Immunohistochemistry on frozen and microwave oven treated paraffin sections (human): 1:500-1:5,000
Immunocytochemistry on transfected cells: 1:500-1:5,000
Immunoprecipitation: 1:500-1:5,000
Optimal working dilutions must be determined by the end user.
Western blot (recombinant protein, not suitable for the natural Huntingtin) : 1:500-1:5,000
Immunohistochemistry on frozen and microwave oven treated paraffin sections (human): 1:500-1:5,000
Immunocytochemistry on transfected cells: 1:500-1:5,000
Immunoprecipitation: 1:500-1:5,000
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
물리적 형태
Ascites fluid. Liquid, does not contain any preservative.
저장 및 안정성
Maintain at -20°C in undiluted aliquots up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.
During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For antibodies with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.
During shipment, small volumes of antibody will occasionally become entrapped in the seal of the product vial. For antibodies with volumes of 200 μl or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
적합한 제품을 찾을 수 없으신가요?
당사의 제품 선택기 도구.을(를) 시도해 보세요.
Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Molecular cloning and characterization of the common marmoset huntingtin gene.
Hirohiko Hohjoh,Hirofumi Akari,Yuko Fujiwara,Yoshiko Tamura,Hirohisa Hirai,Keiji Wada
Gene null
Neurons lacking huntingtin differentially colonize brain and survive in chimeric mice.
A Reiner, N Del Mar, C A Meade, H Yang, I Dragatsis, S Zeitlin, D Goldowitz
The Journal of Neuroscience null
Anjalika Chongtham et al.
Human molecular genetics, 29(4), 674-688 (2020-01-17)
Huntington's disease (HD) is caused by an expansion of a poly glutamine (polyQ) stretch in the huntingtin protein (HTT) that is necessary to cause pathology and formation of HTT aggregates. Here we ask whether expanded polyQ is sufficient to cause
Huntingtin modulates transcription, occupies gene promoters in vivo, and binds directly to DNA in a polyglutamine-dependent manner.
Benn, CL; Sun, T; Sadri-Vakili, G; McFarland, KN; DiRocco, DP; Yohrling, GJ; Clark et al.
The Journal of Neuroscience null
F R Fusco et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 19(4), 1189-1202 (1999-02-10)
Immunohistochemistry and single-cell RT-PCR were used to characterize the localization of huntingtin and/or its mRNA in the major types of striatal neurons and in corticostriatal projection neurons in rats. Single-label immunohistochemical studies revealed that striatum contains scattered large neurons rich
자사의 과학자팀은 생명 과학, 재료 과학, 화학 합성, 크로마토그래피, 분석 및 기타 많은 영역을 포함한 모든 과학 분야에 경험이 있습니다..
고객지원팀으로 연락바랍니다.