추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
purified antibody
항체 생산 유형
primary antibodies
클론
11E4, monoclonal
종 반응성
human
제조업체/상표
Chemicon®
기술
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
동형
IgG1
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... JUP(3728)
특이성
Produced by immunization with recombinant human G-catenin.
애플리케이션
Detect γ-Catenin using this Anti-γ-Catenin Antibody, clone 11E4 validated for use in IP, WB, IC, IH.
Immunohistochemistry: Histochoice fixative is effective.
Immunocytochemistry: Effective for A431 and HT1080 cell lines.
Immunoblotting
Immunoprecipitation
Optimal working dilutions must be determined by end user.
Immunocytochemistry: Effective for A431 and HT1080 cell lines.
Immunoblotting
Immunoprecipitation
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Cytoskeleton
Cytoskeleton
물리적 형태
Format: Purified
Liquid at 1 mg/mL in 0.02 M phosphate buffer, pH 7.6, 0.25M NaCl, containing 0.1% sodium azide.
저장 및 안정성
Maintain refrigerated at 2-8°C in undiluted aliquots for up to12 months.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Characterization of the interactions of alpha-catenin with alpha-actinin and beta-catenin/plakoglobin.
Nieset, J E, et al.
Journal of Cell Science, 110 ( Pt 8), 1013-1022 (1997)
D Salomon et al.
The Journal of cell biology, 139(5), 1325-1335 (1998-01-07)
beta-Catenin and plakoglobin (gamma-catenin) are closely related molecules of the armadillo family of proteins. They are localized at the submembrane plaques of cell-cell adherens junctions where they form independent complexes with classical cadherins and alpha-catenin to establish the link with
P A Sacco et al.
The Journal of biological chemistry, 270(34), 20201-20206 (1995-08-25)
Cadherins are calcium-dependent, cell surface glycoproteins involved in cell-cell adhesion. To function in cell-cell adhesion, the transmembrane cadherin molecule must be associated with the cytoskeleton via cytoplasmic proteins known as catenins. Three catenins, alpha-catenin, beta-catenin, and gamma-catenin (also known as
Cross-talk between adherens junctions and desmosomes depends on plakoglobin.
Lewis, J E, et al.
The Journal of cell biology, 136, 919-934 (1997)
Xuming Mao et al.
The Journal of biological chemistry, 286(2), 1283-1291 (2010-11-17)
Pemphigus vulgaris (PV) is a potentially fatal blistering disease characterized by autoantibodies against the desmosomal adhesion protein desmoglein (Dsg) 3. Whether autoantibody steric hindrance or signaling through pathways such as p38 MAPK is primary in disease pathogenesis is controversial. PV
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