생물학적 소스
mouse
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
BB10, monoclonal
종 반응성
human
제조업체/상표
Chemicon®
기술
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
동형
IgG1
적합성
not suitable for immunohistochemistry (Paraffin)
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... ITGB3(3690)
특이성
Reacts with the beta-3 subunit of the integrin family, including GPIIIa of platelets. Recognized an extracellular epitope of beta-3.
면역원
Partially purified platelet glycoprotein IIb/lIIa complex.
애플리케이션
Anti-Integrin β3 Antibody, clone BB10 is an antibody against Integrin β3 for use in WB, IC, IH.
Immunoblotting: 1:1000 (Ylanne et al., 1988, 1990). The antibody is most effective when used against non-reduced samples.
immunohistochemistry (indirect immunofluorescence)1:200 - 1:400. (Ylanne et al., 1988).
Does not work on paraffin embedded sections.
Final working dilutions must be determined by end user.
immunohistochemistry (indirect immunofluorescence)1:200 - 1:400. (Ylanne et al., 1988).
Does not work on paraffin embedded sections.
Final working dilutions must be determined by end user.
물리적 형태
Format: Purified
Purified immunoglobulin. In PBS with 1% BSA and 0.1% sodium azide.
저장 및 안정성
Maintain between 2 and 8°C up to 12 months.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
External validation suggests Integrin beta 3 as prognostic biomarker in serous ovarian adenocarcinomas.
Partheen, K; Levan, K; Osterberg, L; Claesson, I; Sundfeldt, K; Horvath, G
BMC Cancer null
Functional characterization of integrin alpha6beta4 adhesion interactions using soluble integrin constructs reveals the involvement of different functional domains in the beta4 subunit.
Ling Ling Chen, Veronica Gabarra, Samuel Cho, Beth Browning, Xianjun Cao, Heather Huet et al.
Cell communication & adhesion null
Localization of beta 1, beta 3, alpha 5, alpha v, and alpha IIb subunits of the integrin family in spreading human erythroleukemia cells.
Ylanne, J, et al.
Blood, 76, 570-577 (1990)
Karolina Partheen et al.
International journal of cancer, 123(9), 2130-2137 (2008-08-19)
The mortality rate for patients with ovarian carcinomas is high and the available prognostic factors are insufficient. The use of biomarkers may contribute to better prediction and survival for these patients. We aimed to study the gene and protein expressions
D Seger et al.
The Journal of biological chemistry, 276(20), 16998-17006 (2001-03-30)
Phosphorylation of vitronectin (Vn) by casein kinase II was previously shown to occur at Thr50 and Thr57 and to augment a major physiological function of vitronectin-cell adhesion and spreading. Here we show that this phosphorylation increases cell adhesion via the
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