추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
P1H4, monoclonal
종 반응성
human, primate
제조업체/상표
Chemicon®
기술
ELISA: suitable
flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
동형
IgG1
NCBI 수납 번호
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... ITGA4(3676)
특이성
The involvement of integrins in vascular proliferation, adhesion, and wound repair and have been well-documented. The integrin family of cell adhesion receptors consists of at least 16 membrane-associated heterodimers, composed of an alpha and beta subunit that associate in a non-covalent manner. The structure and functional diversity of the integrin family are based upon the pairing abilities of the individual alpha and beta subunits. Monoclonal antibody MAB16983 was produced by immunization with human T lymphocytes. The antibody is reactive with integrin a4 from primate and human species.
애플리케이션
Anti-Integrin α4 Antibody, clone P1H4 detects level of Integrin α4 & has been published & validated for use in ELISA, FC, IP, IC, IH.
Immunohistochemistry (preferred fixatives are acetone and alcohols)
Immunocytochemistry
Immunoprecipitation
FACS Analysis
ELISA
Radioimmunoassay
Biological Activity: MAB16983 inhibits CS-1 and VCAM binding.
Optimal working dilutions must be determined by end user.
Immunocytochemistry
Immunoprecipitation
FACS Analysis
ELISA
Radioimmunoassay
Biological Activity: MAB16983 inhibits CS-1 and VCAM binding.
Optimal working dilutions must be determined by end user.
결합
Replaces: 04-1131
물리적 형태
Format: Purified
Purified immunoglobulin from Protein A Sepharose™ chromatography. Liquid in 0.02M PB, pH 7.6, 0.25M NaCl containing 0.01% sodium azide.
저장 및 안정성
Maintain at +2-8C.
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Sepharose is a trademark of Cytiva
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
A novel RGD-independent fibronectin assembly pathway initiated by alpha4beta1 integrin binding to the alternatively spliced V region.
J L Sechler, A M Cumiskey, D M Gazzola, J E Schwarzbauer
Journal of Cell Science null
Benjamin Hibbert et al.
Cardiovascular research, 83(1), 16-23 (2009-05-21)
Endothelial progenitor cells (EPCs) are circulating pluripotent vascular cells capable of enhancing re-endothelialization and diminishing neointima formation following arterial injury. Glycogen synthase kinase (GSK)-3beta is a protein kinase that has been implicated in the regulation of progenitor cell biology. We
Integrin alpha9beta1 mediates enhanced cell migration through nitric oxide synthase activity regulated by Src tyrosine kinase.
Gupta, SK; Vlahakis, NE
Journal of Cell Science null
PKCepsilon regulation of an alpha5 integrin-ZO-1 complex controls lamellae formation in migrating cancer cells.
Tuomi S, Mai A, Nevo J, Laine JO, Vilkki V, Ohman TJ, Gahmberg CG, Parker PJ, Ivaska J
Science Signaling null
Rika Tanaka et al.
The Journal of biological chemistry, 284(30), 19817-19825 (2009-05-23)
Fibronectin plays important roles in erythropoiesis through the fibronectin receptors VLA-4 and VLA-5. However, the substantial role of these fibronectin receptors and their functional assignment in erythroid differentiation are not yet fully understood. Here, we investigated the effects of cell
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