추천 제품
생물학적 소스
mouse
Quality Level
항체 형태
purified immunoglobulin
항체 생산 유형
primary antibodies
클론
195, monoclonal
종 반응성
human
반응하면 안 됨
pig, monkey, canine, mouse, rat, baboon
포장
antibody small pack of 25 μg
제조업체/상표
Chemicon®
기술
immunocytochemistry: suitable
immunohistochemistry: suitable
neutralization: suitable
western blot: suitable
동형
IgG3
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
저장 온도
−20°C
타겟 번역 후 변형
unmodified
유전자 정보
human ... TNF(7124)
관련 카테고리
특이성
The antibody reacts with human, natural and recombinant TNF-alpha. lt does not react with human TNF-beta (lymphotoxin). lt does not react with TNF-alpha from mouse, rat, canine, porcine, rhesus-monkey or baboon.
SPECIES REACTIVITIES:
Not mouse, rat, canine, porcine, baboon or rhesus-monkey.
SPECIES REACTIVITIES:
Not mouse, rat, canine, porcine, baboon or rhesus-monkey.
면역원
Human, recombinant tumor necrosis factor-alpha produced in E. coli.
애플리케이션
Research Category
Signaling
Signaling
Research Sub Category
Growth Factors & Receptors
Growth Factors & Receptors
This Anti-Tumor Necrosis Factor-α Antibody, clone 195 is validated for use in IC, IH, NEUT, WB for the detection of Tumor Necrosis Factor-α.
Western Blot
Immunocytochemistry
Immunohistochemistry
Neutralization: 50 ng of TNF-alpha antibody is required for the neutralization of 1 U TNF-alpha. The TNF-alpha-preparation which is used has a specific activity of 2 x 10(7) U/mg protein [cell lytic assay with L929 cells (mouse transformed fibroblasts) and/or WEHJ 164 cells (mouse fibrosarcoma cells)/actinomycin D].
Optimal working dilutions must be determined by end user.
Immunocytochemistry
Immunohistochemistry
Neutralization: 50 ng of TNF-alpha antibody is required for the neutralization of 1 U TNF-alpha. The TNF-alpha-preparation which is used has a specific activity of 2 x 10(7) U/mg protein [cell lytic assay with L929 cells (mouse transformed fibroblasts) and/or WEHJ 164 cells (mouse fibrosarcoma cells)/actinomycin D].
Optimal working dilutions must be determined by end user.
결합
Replaces: 04-1114
물리적 형태
Format: Purified
Purified immunoglobulin. Liquid in 0.01M PBS pH 7.1, 0.15M NaCl containing no preservatives. Sterile filtered.
저장 및 안정성
Maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. Freeze only once.
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
Mei Liu et al.
International journal of oncology, 38(4), 1013-1022 (2011-01-29)
Many studies have demonstrated the overexpression and amplification of the miR-17-92 cluster in malignant human cancers, including B-cell lymphomas and lung cancers. The purpose of this study was to investigate for the first time, the expression of the miR-17-92 cluster
Micaela Morgado et al.
Oncotarget, 7(12), 14871-14884 (2016-02-27)
Transmembrane mucins (TMs) are restricted to the apical surface of normal epithelia. In cancer, TMs not only are over-expressed, but also lose polarized distribution. MUC16/CA125 is a high molecular weight TM carrying the CA125 epitope, a well-known molecular marker for
Acute bronchial obstruction in sheep: histopathology and gland cytokine expression.
Robert A Cox, Ann S Burke, Gloria Oliveras, Perenlei Enkhbaatar, Lillian D Traber et al.
Experimental Lung Research null
Monocyte-mediated drug-dependent cellular cytotoxicity: effects on different WEHI 164 target cell lines.
Austgulen, R, et al.
Cancer Immunology, Immunotherapy, 22, 176-180 (1986)
Human lymphotoxin.
Aggarwal, B B
Test, 116, 441-448 (1985)
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