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Merck
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Key Documents

GF176

Sigma-Aldrich

TGF-β-III Protein, Human Recombinant

TGF-β-III (transforming growth factor beta III) is one of three closely related mammalian members of the large TGF-β superfamily.

동의어(들):

Transforming Growth Factor Beta 3, TGF-Beta-3, TGF-Beta-III

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About This Item

UNSPSC 코드:
12352202
eCl@ss:
32160405
NACRES:
NA.77

Quality Level

분석

>98% (SDS-PAGE and HPLC)

불순물

<0.1 μg/mg protein endotoxin (<1 EU/μg)

UniProt 수납 번호

배송 상태

dry ice

유전자 정보

human ... TGFB3(7043)

일반 설명

Product Source: E. coli.
TGF-β-III (transforming growth factor beta III) is one of three closely related mammalian members of the large TGF-β superfamily. TGF-β-I, TGF-β-II and TGF-β-III are highly pleiotropic cytokines that are proposed to act as cellular switches that regulate processes such as immune function, proliferation and epithelial mesenchymal transition. TGF-β3 regulates molecules involved in cellular adhesion and extracellular matrix formation during the process of palate development. TGF-β3 also plays an essential role in controlling the development of lungs in mammals and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. Recombinant TGF-β-III is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.

애플리케이션

Research Category
Stem Cell Research
Research Sub Category
Growth Factors & Receptors

품질

Determined by TGF-β-III’s ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.

물리적 형태

Product is filtered through a 0.2 micron filter before lyophilization.

저장 및 안정성

Store at -20°C for up to 6 months from date of receipt.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


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