FCMAB198F

Milli-Mark^® Anti-CD54-FITC Antibody, clone 6.5B5

clone 6.5B5, Milli-Mark^®, from mouse

• 동의어(들): Intercellular adhesion molecule 1, ICAM-1, Major group rhinovirus receptor
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.44

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: FITC conjugate
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: 6.5B5, monoclonal
• 종 반응성: human
• 제조업체/상표: Milli-Mark^®
• 기술: flow cytometry: suitable
• 동형: IgG1κ
• NCBI 수납 번호: NP_000192
• UniProt 수납 번호: P05362
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... ICAM1(3383)

설명

일반 설명

The CD54 antigen is a single chain glycoprotein with a molecular mass of 90 kDa (Springer, 1990). It is the human intercellular adhesion molecule-1 (ICAM-1) belonging to the immunoglobulin supergene family. The ligand for ICAM-1 is LFA-1 (leucocyte function associated-1 protein) (Berendt, 1992). ICAM-1 is widely expressed on many cell types, although the degree of expression by unstimulated resting cells varies. As a cellular activation antigen the expression of ICAM-1 is up-regulated upon cell activation, being induced particularly in response to cytokines such as interleukin-1, tumor necrosis factor, and interferon- (Berendt, 1992; Wellicome, 1990; Thornhill, 1990). ICAM-1 might be a receptor for rhinovirus (Staunton, 1989). In rejecting kidneys the antibody stains all infiltrating cells strongly as well as glomerulus epithelium, endothelium on capillaries, large vessels, and mesangium (Waugh, 1989).

특이성

Antibody recognizes Human CD54 antigen.

면역원

TNF-activated human umbilical vein endothelial cells

애플리케이션

Milli-Mark Anti-CD54-FITC Antibody, clone 6.5B5 is an antibody against CD54 for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

품질

Evaluated by flow cytometry using human lymphocytes

표적 설명

90 kDa (Springer, 1990)

물리적 형태

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

저장 및 안정성

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

분석 메모

Control
Human Lymphocytes

법적 정보

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable