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Key Documents

FCABS301A4

Sigma-Aldrich

Milli-Mark® Anti-dimethyl-Histone H3 (Lys9)-Alexa Fluor488 Antibody

Milli-Mark®, from rabbit

동의어(들):

H3 histone family, member T, histone 3, H3, histone cluster 3, H3

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

결합

ALEXA FLUOR 488

항체 형태

purified immunoglobulin

항체 생산 유형

primary antibodies

클론

polyclonal

종 반응성

human

제조업체/상표

Milli-Mark®

기술

flow cytometry: suitable

동형

IgG

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

dimethylation (Lys9)

유전자 정보

human ... H3C1(8350)

일반 설명

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

특이성

Antibody recognizes human Histone H3 dimethylated on lysine 9.

면역원

Epitope: Methylated at Lys9dimethylated Lys 9 of Human Histone H3
KLH-conjugated, 2X-branched synthetic peptide corresponding to dimethyl-lysine at residue 9 of human Histone H3.

애플리케이션

Milli-Mark Anti-dimethyl-Histone H3 (Lys9)-Alexa Fluor488 Antibody detects level of dimethyl-Histone H3 (Lys9)-Alexa Fluor488 & has been published & validated for use in FC.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Histones

품질

Evaluated by flow cytometry using HeLa cells

표적 설명

15.5 kDa Calculated

물리적 형태

Protein A purified
Purified rabbit polyclonal IgG conjugated to Alexa Fluor 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA

저장 및 안정성

Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.

분석 메모

Control
HeLa Cells

법적 정보

ALEXA FLUOR is a trademark of Life Technologies
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Valeria Barili et al.
Nature communications, 11(1), 604-604 (2020-02-01)
Hepatitis C virus infection (HCV) represents a unique model to characterize, from early to late stages of infection, the T cell differentiation process leading to exhaustion of human CD8+ T cells. Here we show that in early HCV infection, exhaustion-committed

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