CBL412A5

Anti-Tubulin β-III Antibody, clone TU-20, Alexa Fluor^™555 Conjugate

clone TU-20, from mouse, ALEXA FLUOR^™ 555

• 동의어(들): Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: mouse
• Quality Level: 100
• 결합: ALEXA FLUOR^™ 555
• 항체 형태: purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: TU-20, monoclonal
• 종 반응성: rat, pig
• 종 반응성(상동성에 의해 예측): primate (based on 100% sequence homology), bovine (based on 100% sequence homology), mouse (based on 100% sequence homology), porcine (based on 100% sequence homology)
• 기술: immunocytochemistry: suitable
• 동형: IgG1
• NCBI 수납 번호: NP_001184110
• UniProt 수납 번호: Q13509
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: mouse ... Tubb3(22152)

설명

일반 설명

Tubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions.

특이성

This antibody reacts with the C-terminus of the beta-III isoform of tubulin, which is known to be neuron specific. Does not identify beta tubulin found in glial cells.

면역원

Epitope: C-terminus

Synthetic peptide corresponding to human Tubulin β-III.

애플리케이션

Detect Tubulin β-III using this Anti-Tubulin β-III Antibody, clone TU-20, Alexa Fluor^™555 Conjugate validated for use in ICC.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

품질

Evaluated by Immunocytochemistry in rat E18 primary cortex cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Tubulin β-III in rat E18 primary cortex cells.

표적 설명

The unconjugated parent antibody (Cat. No. MAB1637) has an observed molecular weight at ~55 kDa

물리적 형태

Protein G Purified

Purified mouse monoclonal IgG1 conjugated to Alexa Fluor^™ 555 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

저장 및 안정성

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

분석 메모

Control
Rat E18 primary cortex cells

법적 정보

ALEXA FLUOR is a trademark of Life Technologies

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable