추천 제품
생물학적 소스
goat
Quality Level
결합
peroxidase conjugate
항체 형태
affinity purified immunoglobulin
항체 생산 유형
secondary antibodies
클론
polyclonal
양식
lyophilized
종 반응성
human
제조업체/상표
Chemicon®
농도
1.0 mg/mL
기술
ELISA: suitable
western blot: suitable
동형
IgG
배송 상태
wet ice
저장 온도
2-8°C
타겟 번역 후 변형
unmodified
일반 설명
Immunoglobulin G (IgG) is the main type of glycoprotein antibody found in human serum, secreted by the B cells. It is found in blood and comprises four polypeptide chains, made of two identical 50 kDa γ heavy (H) chains and two identical 25 kDa κ or λ light (L) chains. These chains are inter-linked by di-sulfide bonds. IgG exists in four isotypes IgG1, IgG2, IgG3 and IgG4. IgG has the longest serum half-life compared to other immunoglobulins.
특이성
Specific for human IgG gamma chain. The cross-reactivities of anti-human IgG (gamma) antibody are tested in an ELISA. Minimal cross-reactivity to light chains.
The reagent is an affinity purified antibody from goat. The purified antibody is conjugated to horseradish peroxidase (HRP) and stabilized in buffer.
The reagent is an affinity purified antibody from goat. The purified antibody is conjugated to horseradish peroxidase (HRP) and stabilized in buffer.
애플리케이션
ELISA: 1:3,000
Immunohistochemistry: 1:200-1:500 (1-4)
Immunocytochemistry: 1:200-1:500 (1-4)
Western Blot, chromogenic: 1:200-1-500
Western Blot, chemiluminescent: 1:2,000-1:5,000
Optimal working dilutions must be determined by the end user.
Immunohistochemistry: 1:200-1:500 (1-4)
Immunocytochemistry: 1:200-1:500 (1-4)
Western Blot, chromogenic: 1:200-1-500
Western Blot, chemiluminescent: 1:2,000-1:5,000
Optimal working dilutions must be determined by the end user.
생화학적/생리학적 작용
Immunoglobulin G (IgG) initiates the classical pathway of the complement system. It neutralizes virus particles and toxins. IgG plays a vital role in antibody-dependent cell-mediated cytotoxicity (ADCC) and might be associated with allergy. Maternal IgG is transferred to the fetus through the placenta that is crucial for the immune defense of the neonate against infections. Digestion of IgG by papain results in the production of fragment antigen-binding (Fab). Pepsin digestion of IgG leads to the generation of fragment crystallizable (Fc). Levels of IgG in severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infected patients can be used as a potential tool to evaluate the severity and prognosis of coronavirus disease 2019 (COVID-19).
물리적 형태
ImmunoAffinity Purified
0.01M PBS, PH7.1, with 15mg/mL BSA
0.01M PBS, PH7.1, with 15mg/mL BSA
저장 및 안정성
The undiluted antibody is stable at 2-8°C for 12 months. Do not store in a diluted format. DO NOT FREEZE.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
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