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Merck
모든 사진(1)

주요 문서

AG714

Sigma-Aldrich

Human IgG, Fc Fragment

동의어(들):

IgG Fc Fragment

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

human

Quality Level

항체 형태

purified immunoglobulin

제조업체/상표

Chemicon®

배송 상태

wet ice

타겟 번역 후 변형

unmodified

일반 설명

Product Source: Human serum. Tested by an FDA approved test method and found negative for HIV antibody, Hepatitis B Surface Antigen, antibody to Hepatitis C and syphilis.

애플리케이션

Research Category
Controls

물리적 형태

Format: Purified
Sterile liquid in 0.01 M Sodium Phosphate, 0.25 M NaCl, pH 7.6. No preservatives have been added.

저장 및 안정성

Store under sterile conditions at +2-8°C for up to one year. Dilute only as needed for a single day′s use.

분석 메모

Single precipitin line by immunoelectrophoresis at 20 mg/mL against Goat anti-Human whole serum. No cross-reactivity against Goat anti-Human IgG F(ab′)2 fragment, IgM, Fc(5μ) or IgA, alpha-chain specific. Purified by column chromatography.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Iftiin Hassan Mohamed et al.
Pharmacological research, 64(5), 464-470 (2011-07-12)
The Eph tyrosine kinase receptors and their ephrin ligands play a central role in several human cancers and their deregulated expression or function promotes tumorigenesis, inducing aggressive tumor phenotypes. Green tea extracts (GTE) have been recently found to inhibit Eph-kinase
Sara C Humphreys et al.
Drug metabolism and disposition: the biological fate of chemicals, 47(10), 1174-1182 (2019-05-18)
Understanding small interfering RNA (siRNA) fraction unbound (f u) in relevant physiologic compartments is critical for establishing pharmacokinetic-pharmacodynamic relationships for this emerging modality. In our attempts to isolate the equilibrium free fraction of N-acetylgalactosamine-conjugated siRNA using classic small-molecule in vitro
Anabel Gonzalez-Gil et al.
The Journal of allergy and clinical immunology, 147(4), 1442-1452 (2020-08-14)
The immunoinhibitory receptor Siglec-8 on the surface of human eosinophils and mast cells binds to sialic acid-containing ligands in the local milieu, resulting in eosinophil apoptosis, inhibition of mast cell degranulation, and suppression of inflammation. Siglec-8 ligands were found on
Christian Henneberger et al.
Neuron, 108(5), 919-936 (2020-09-26)
Extrasynaptic actions of glutamate are limited by high-affinity transporters expressed by perisynaptic astroglial processes (PAPs): this helps maintain point-to-point transmission in excitatory circuits. Memory formation in the brain is associated with synaptic remodeling, but how this affects PAPs and therefore
Massimiliano Tognolini et al.
ChemMedChem, 7(6), 1071-1083 (2012-04-25)
The Eph-ephrin system, including the EphA2 receptor and the ephrinA1 ligand, plays a critical role in tumor and vascular functions during carcinogenesis. We previously identified (3α,5β)-3-hydroxycholan-24-oic acid (lithocholic acid) as an Eph-ephrin antagonist that is able to inhibit EphA2 receptor

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