추천 제품
생물학적 소스
chicken
Quality Level
형태
liquid
제조업체/상표
Chemicon®
농도
100 μg/mL
기술
ELISA: suitable
cell culture | mammalian: suitable
NCBI 수납 번호
UniProt 수납 번호
배송 상태
dry ice
유전자 정보
chicken ... NCAN(395493)
일반 설명
Neurocan, chicken.
Product Source: Chicken Brain.
애플리케이션
Inhibition of cell-cell adhesion, cell-ECM adhesion or cell migration at:
0.1 to 30 micrograms / mL.
ELISA Assay: 0.05 to 5 micrograms / mL
Optimal working concentrations must be determined by the end user.
0.1 to 30 micrograms / mL.
ELISA Assay: 0.05 to 5 micrograms / mL
Optimal working concentrations must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
물리적 형태
Purified Neurocan in PBS. Contains no preservative.
저장 및 안정성
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
분석 메모
A mix of Chondroitin Sulfate Proteoglycans from chick brain (Chemicon CC117) was purified by the unique density and size of this class of molecules. Neurocan is purified from this mix using an immobilized monoclonal antibody. The resulting neurocan is pure and has chondroitin sulfate attached. Removing the chondroitin sulfate with chondroitinase, results in core proteins are primarily the full-length 250 kD form and a little of smaller neurocan fragments.
법적 정보
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
H Ernst et al.
Journal of cell science, 108 ( Pt 12), 3807-3816 (1995-12-01)
Chondroitin sulfate proteoglycans inhibit the adhesion of cells to extracellular matrix proteins that otherwise permit adhesion. Although proteoglycans are widely assumed to act by masking the other protein in a mixed substrate, recent studies suggest that proteoglycans inhibit adhesion through
The interaction of the retina cell surface N-acetylgalactosaminylphosphotransferase with an endogenous proteoglycan ligand results in inhibition of cadherin-mediated adhesion.
Balsamo, J, et al.
The Journal of cell biology, 129, 1391-1401 (1995)
MMP and non-MMP-mediated release of aggrecan and its fragments from articular cartilage: a comparative study of three different aggrecan and glycosaminoglycan assays.
E U Sumer, B C Sondergaard, J C Rousseau, P D Delmas, A J Fosang, M A Karsdal et al.
Osteoarthritis and Cartilage / OARS, Osteoarthritis Research Society null
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