ABT69

Anti-CCDC53 Antibody

from rabbit

• 동의어(들): coiled-coil domain containing 53, Coiled-coil domain-containing protein 53, WASH complex subunit CCDC53
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: purified antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 종 반응성: human, rat, mouse
• 기술: western blot: suitable
• NCBI 수납 번호: NP_057137
• UniProt 수납 번호: Q9Y3C0
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... CCDC53(51019)

설명

일반 설명

Coiled-coil domain-containing protein 53 (CCDC53) is one of several components comprising the WASH complex, a complex localized to endosomal surfaces that functions to upregulate actin polymerization through the recruiting and activation of Arp2/3 complex. WASH is a critical component in the fission of tubules (transport intermediates involved in the distribution of endosomes). The WASH complex is composed of CCDC53, F-actin-capping protein subunits alpha and beta, WASH, FAM21, KIAA1033, and KIAA196.

면역원

GST-tagged recombinant protein corresponding to human CCDC53.

애플리케이션

Research Category
Cell Structure

Research Sub Category
Cytoskeletal Signaling

This Anti-CCDC53 Antibody is validated for use in WB for the detection of CCDC53.

Western Blot Analysis: 2.5 µg/mL from a representative lot detected CCDC53 in 10 µg of mouse brain and PC12 cell lysate.

품질

Evaluated by Western Blot in HepG2 cell lysate.

Western Blot Analysis: 2.5 µg/mL of this antibody detected CCDC53 in 10 µg of HepG2 cell lysate.

표적 설명

~28 kDa observed

물리적 형태

Format: Purified

Protein G Purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
HepG2 cell lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable