ABT407

Anti-MYOZAP Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): Myocardial zonula adherens protein, GRINL1A upstream protein, Gup
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: rat
• 기술: western blot: suitable
• UniProt 수납 번호: P0CAP1
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified

설명

일반 설명

Myocardial zonula adherens protein, also known as GRINL1A upstream protein (Gup), and encoded by the gene name MYZAP or MYOZAP, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase–RhoA interacting protein (MRIP) and acts as an activator of Rhodependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, Nmethyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts and Gcom for GRINL1A combined transcripts.

면역원

Epitope: C-terminus

KLH-conjugated synthetic peptide corresponding to the C-terminus of human MYOZAP.

애플리케이션

Anti-MYOZAP Antibody detects level of MYOZAP & has been published & validated for use in MYOZAP.

Research Category
Cell Structure

Research Sub Category
Cytoskeleton

품질

Evaluated by Western Blotting in rat kidney tissue lysate.

Western Blotting Analysis: 1 μg/mL of this antibody detected MYOZAP in rat kidney tissue lysate.

표적 설명

~54 kDa observed. Uncharacterized bands may be observed in some lysate(s). Uniprot describes 11 isoforms produced by alternative splicing ranging between ~44 kDa and ~54 kDa

물리적 형태

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable