ABT148

Anti-Claudin-11 Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): Claudin-11, Oligodendrocyte-specific protein
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human
• 종 반응성(상동성에 의해 예측): chimpanzee (based on 100% sequence homology)
• 기술: western blot: suitable
• NCBI 수납 번호: NP_005593
• UniProt 수납 번호: O75508
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... CLDN11(5010)

설명

일반 설명

Claudin-11 (CLDN11; or Oligodendrocyte-specific protein) is expressed in Sertoli cells of the testis. It is involved in the formation of tight junctions, which is required for spermatogenesis. Previous studies have indicated that claudin-11 may prevent the progression of bladder cancer by blocking cell invasion and metastatis.

특이성

Other homologies: Mouse and Rat (93% sequence homology).

This antibody recognizes the cytoplasmic domain of Claudin-11.

면역원

Epitope: Cytoplasmic domain

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Claudin-11.

애플리케이션

Anti-Claudin-11 Antibody is an antibody against Claudin-11 for use in Western Blotting.

Research Category
Cell Structure

Research Sub Category
ECM Proteins

Western Blot Analysis: 1 µg/mL from a representative lot detected Claudin-11 in human kidney tissue lysate.

Western Blot Analysis: 2 µg/mL from a representative lot detected Claudin-11 in human testis tissue lysate.

품질

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Claudin-11 in 10 µg of human brain tissue lysate.

표적 설명

~22 kDa observed. An uncharacterized band may be observed at ~60 kDa in some tissue lysates.

물리적 형태

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
Human brain tissue lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable