ABS72

Anti-WAS protein family homolog 1 (CT) Antibody

from rabbit

• 동의어(들): WAS protein family homolog 1, family with sequence similarity 39, member E, CXYorf1-like protein on chromosome 2, Protein FAM39E
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: purified antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 종 반응성: mouse, human
• 기술: western blot: suitable
• 동형: IgG
• NCBI 수납 번호: NP_878908
• UniProt 수납 번호: A8K0Z3
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... WASH1(100287171)

설명

일반 설명

Wiskott-Aldrich Syndrome Protein and SCAR Homolog (WASH) is a novel protein belonging to the WASP family, a group of nucleation promoting factors (NFPs) that activate a critical component in endocytosis, Arp 2/3. WASH contains three specific domains: a C-terminal VCA domain, a proline-rich domain, and an N terminal region containing two WASH homolog regions, WHD1 and WHD2. Although WASH has yet to be completely characterized, it is known to function as an NPF at the endosomal surface, where it is involved in the recruitment and subsequent activation of Arp2/3 in order to initiate actin polymerization. Therefore, WASH has a crucial role in endosomal sorting as a mediator of tubule fission resulting from Arp2/3 activation.

특이성

This antibody recognizes WAS protein family homolog 1 at the C-terminus.

면역원

Epitope: C-terminus

GST-tagged recombinant protein corresponding to human WAS protein family homolog 1 at the C-terminus.

애플리케이션

Anti-WAS protein family homolog 1 (C-terminus) Antibody detects level of WAS protein family homolog 1 (C-terminus) & has been published & validated for use in WB.

Research Category
Signaling

품질

Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected WAS protein family homolog 1 on 10 µg of HeLa cell lysate.

표적 설명

~ 60 kDa observed. The calculated molecular weight is 50 kDa

물리적 형태

Format: Purified

Protein G

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
HeLa cell lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable