ABS564

Anti-Serpinf2 Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): Alpha-2-antiplasmin, Alpha-2-AP, Alpha-2-plasmin inhibitor, Alpha-2-PI, Serpin F2
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human
• 종 반응성(상동성에 의해 예측): primate (based on 100% sequence homology)
• 기술: immunohistochemistry: suitable; western blot: suitable
• NCBI 수납 번호: NP_000925
• UniProt 수납 번호: P08697
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... SERPINF2(5345)

설명

일반 설명

Serpin F2, also known as Alpha-2-antiplasmin Alpha-2-AP, Alpha-2-plasmin inhibitor, Alpha-2-PI, and encoded by the gene name SERPINF2, AAP, or PLI, is a member of the Serpin family. Serpin F2 is a serine protease inhibitor. As an inhibitor, the major targets of Serpin F2 are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin. Serpin F2 forms protease inhibiting heterodimer with TMPRSS7. Serpin F2 is expressed by the liver and secreted in plasma. Mutations in Serpin F2 have been associated with Alpha-2-plasmin inhibitor deficiency (APLID), an autosomal recessive disorder resulting in severe hemorrhagic diathesis.

면역원

Epitope: Alpha-2-antiplasmin mature chain

KLH-conjugated linear peptide corresponding to the Alpha-2-antiplasmin mature chain of human Serpinf2.

애플리케이션

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Serpinf2 in human liver and human liver cancer tissue.

Research Category
Signaling

Research Sub Category
Signaling Neuroscience

This Anti-Serpinf2 antibody is validated for use in WB, IH for the detection of Serpinf2.

품질

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected Serpinf2 in 10 µg of human liver tissue lysate.

표적 설명

~73 kDa observed. Predicated to work with both glycos and non-glycos isoforms.

물리적 형태

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

기타 정보

Concentration: Please refer to lot specific datasheet.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1