ABN457

Anti-Peptide YY Antibody

from chicken, purified by affinity chromatography

• 동의어(들): Peptide YY1, PYYPYY-I, Peptide tyrosine tyrosine, Peptide YY(3-36), PYY-II, Peptide YY
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: chicken
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: rat, mouse
• 기술: immunohistochemistry: suitable; western blot: suitable
• 동형: IgY
• NCBI 수납 번호: NP_004151
• UniProt 수납 번호: P10082
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: mouse ... Pyy(217212) ; rat ... Pyy(287730)

설명

일반 설명

Peptide YY (UniProt P10082; also known as Peptide tyrosine tyrosine, PYY, PYY-I) is encoded by the PYY (also known as PYY1) gene (Gene ID 5697) in human. Peptide YY is initially produced as a preproprotein with a signal and a propeptide sequence (aa 1-28 and aa 68-97, respectively). There are two major forms of mature peptide YY corresponding to aa 29-64 and aa 31-64 of the prepro sequence, commonly known as YY(1-36) and YY(3-36), respectively. PYY is one of several well recognized circulating anorexigenic peptides, whose productions increase post-prandially. PYY and glucagon-like peptide 1 (GLP-1) are released from L cells that predominate in the distal ileum and colon. The melanocortin-4 receptor (MC4R) is reported to mediate PYY and GLP-1 release from enteroendocrine L cells upon melanocortin peptides stimulation.

특이성

Reacts with prepro-, pro-, and mature peptide YY & peptide YY(3-36).

면역원

Epitope: Mature Peptide YY

KLH-conjugated linear peptide corresponding to the mature human peptide YY.

애플리케이션

Anti-Peptide YY Antibody, Cat. No. ABN457, is a highly specific chicken Polyclonal antibody, that targets Peptide YY and has been tested in Western Blotting, Immunohistochemistry.

Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Peptide YY in rat colon tissue.

품질

Evaluated by Western Blotting in rat small intestine tissue lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected Peptide YY in 10 µg of rat small intestine tissue lysate.

표적 설명

~11 kDa observed

기타 정보

Concentration: Please refer to lot specific datasheet.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable