ABN16

Anti-GPR56 Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): G protein-coupled receptor 56, 7-transmembrane protein with no EGF-like N-terminal domains-1, Protein TM7XN1, G-protein coupled receptor 56
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: mouse
• 기술: immunohistochemistry: suitable
• 동형: IgG
• NCBI 수납 번호: NP_061370
• UniProt 수납 번호: Q8K209
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... GPR56(9289)

설명

일반 설명

G-protein coupled receptor 56 (GPR56) is a novel, multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and containing a characteristic, extracellular GPS domain. Although newly discovered, studies have suggested roles for the protein in the adhesion between developing neurons, regulating the integrity of pial basement membranes, regulating corticogenesis, and may also be involved in cancer cell metastasis and adhesion. Expression has been observed in a wide variety of peripheral tissues, but the most significant levels have been reported in brain, heart, and thyroid gland. Defects in GPR56 expression cause bilateral frontoparietal polymicrogyria (BFPP), a malformation of the brain in humans that is characterized by ataxia, seizures, disfigurement of the cerebral cortex, and mental retardation.

특이성

This antibody recognizes GPR56 at the N-terminus.

면역원

Epitope: N-terminus

Linear peptide corresponding to the N-terminus sequence of mouse GPR56.

애플리케이션

Detect GPR56 using this Anti-GPR56 Antibody validated for use in IH.

Immunohistochemistry Analysis: 1:200 dilution of this antibody from a previous lot detected GPR56 in anal carcinoma and testicular teratoma tissue.

Research Category
Neuroscience

Neuroscience

Research Sub Category
Neurodegenerative Diseases

Neurotransmitters & Receptors

품질

Evaluated by Immunohistochemistry in inflammatory skin biopsy tissue.

Immunohistochemistry Analysis: 1:200 dilution of this antibody detected GPR56 in inflammatory skin biopsy tissue.

표적 설명

77 kDa calculated

물리적 형태

Affinity purified

Purified rabbit polyclonal in buffer containing 0.05% sodium azide with 50% Glycerol.

저장 및 안정성

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

분석 메모

Control
Inflammatory skin biopsy tissue

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2