ABN1347M

Anti-Glutathione S-transferase A5 (GSTA5)

from rabbit, purified by affinity chromatography

• 동의어(들): EC:2.5.1.18, GST class-alpha member 5, Glutathione S-transferase A5-5, Glutathione S-transferase alpha 5
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human
• 종 반응성(상동성에 의해 예측): monkey (based on 100% sequence homology)
• 포장: antibody small pack of 25 μL
• 기술: immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBI 수납 번호: NM_153699.1
• UniProt 수납 번호: Q7RTV2
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... GSTA5(221357)

설명

일반 설명

Glutathione S-transferase A5 (UniProt: Q7RTV2; also known as EC: 2.5.1.18, GST class-alpha member 5, Glutathione S-transferase A5-5) is encoded by the GSTA5 gene (Gene ID: 221357) in human. Glutathione S-transferases are soluble proteins that catalyze the conjugation of reduced glutathione and a variety of electrophiles, including many known carcinogens and mutagens. Glutathione S-transferase A5 is a homodimeric cytoplasmic protein with two glutathione binding sites. The mammalian glutathione S-transferases are active in drug metabolism are classified into the alpha, mu and pi classes. Members of the alpha-class of glutathione S-transferases show substrate specificity for cumene hydroperoxide (CuOOH) and 7-chloro-4-nitrobenz-2-oxa-1, 3-diazole (NBD-C1). They exhibit a number of differences from the characteristic glutathione S-transferase structure. For example, in its domain II, it contains a short 3-residue beta-strand near the C-terminal segment and a longer alpha-7 helix.

특이성

This rabbit polyclonal antibody detects Glutathione S-transferase A5 in Human Liver. It targets an epitope within 14 amino acids from the internal region.

면역원

KLH-conjugated linear peptide corresponding to 14 amino acids from the internal region of human Glutathione S-transferase A5.

애플리케이션

Anti-Glutathione S-transferase A5 (GSTA5) Antibody, Cat. No. ABN1347, is a highly specific rabbit polyclonal antibody that detects human Glutathione S-transferase A5 and has been tested in Immunohistochemistry (Paraffin) and Western Blotting.

Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Glutathione S-transferase A5 (GSTA5) in human liver tissue.

Research Category
Neuroscience

품질

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: A 1:2,000 dilution of this antibody detected Glutathione S-transferase A5 (GSTA5) in human liver tissue lysate.

표적 설명

~25 kDa observed; 25.72 kDa calculated. Uncharacterized bands may be observed in some lysate(s).

물리적 형태

Affinity Purified

Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

기타 정보

Concentration: Please refer to lot specific datasheet.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1