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Merck
모든 사진(2)

Key Documents

ABE600

Sigma-Aldrich

Anti-SATB2 Antibody

from rabbit, purified by affinity chromatography

동의어(들):

DNA-binding protein SATB2, Special AT-rich sequence-binding protein 2

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

정제법

affinity chromatography

종 반응성

human, mouse

기술

immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... SATB2(23314)

일반 설명

Special AT-rich sequence-binding protein 2 (SATB2) contains 2 CUT DNA-binding domains and one homeobox DNA binding domain belonging to the CUT homeobox family. SATB2 binds to DNA at the nuclear matri or scaffold-associated regions. SATB2 is highly expressed in adult brain, moderately expressed in fetal brain, and weakly expressed in adult liver, kidney, and spinal cord. Mutations in SATB2 have been associated with cleft palate.

특이성

This antibody recognizes the N-terminus of SATB2.

면역원

Epitope: N-terminus
KLH-conjugated linear peptide corresponding to the N-terminus of human SATB2.

애플리케이션

Detect Special AT-rich sequence-binding protein 2 using this rabbit polyclonal antibody, Anti-SATB2 Antibody validated for use in western blotting, IHC (Paraffin) & Immunofluorescence.
Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected SATB2 in human brain tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected SATB2 in human brain cells.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors

품질

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 4 µg/mL of this antibody detected SATB2 in 15 µg of mouse brain tissue lysate.

표적 설명

~90 kDa observed

물리적 형태

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
Mouse brain tissue lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Lei Wang et al.
Nature neuroscience, 19(7), 888-896 (2016-05-24)
The unique mental abilities of humans are rooted in the immensely expanded and folded neocortex, which reflects the expansion of neural progenitors, especially basal progenitors including basal radial glia (bRGs) and intermediate progenitor cells (IPCs). We found that constitutively active

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