ABE409

Anti-UTX Antibody

from rabbit, purified by affinity chromatography

• 동의어(들): Lysine-specific demethylase 6A, Histone demethylase UTX, Ubiquitously-transcribed TPR protein on the X chromosome, Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity isolated antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: human, mouse
• 종 반응성(상동성에 의해 예측): chimpanzee (based on 100% sequence homology)
• 기술: immunocytochemistry: suitable; western blot: suitable
• NCBI 수납 번호: NP_066963
• UniProt 수납 번호: O15550
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... KDM6A(7403)

설명

일반 설명

Histone demethylase UTX is also known as Lysine-specific demethylase 6A, Ubiquitously-transcribed TPR protein on the X chromosome, and Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein. UTX is a histone demethylase that specifically demethylates trimethylated and dimethylated but not monomethylated histone H3 ′Lys-27′. UTX is involved in regulation of posterior development, and defects can cause Kabuki syndrome type 2 (KABUK2)

특이성

Other homologies: Canine (99% sequence homology) and Bovine (96% sequence homology).

면역원

GST-tagged recombinant protein corresponding to human UTX.

애플리케이션

Detect Histone demethylase UTX using this rabbit polyclonal antibody, Anti-UTX Antibody validated for use in western blotting & ICC.

Immunocytochemistry Analysis: A 1:50 dilution from a representative lot detected UTX in HeLa, A431, and 3T3 cells.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Chromatin Biology

품질

Evaluated by Western Blotting in HeLa nuclear extract.

Western Blotting Analysis: 0.5 µg/mL of this antibody detected UTX in 10 µg of HeLa nuclear extract.

표적 설명

~154 kDa observed. Uncharacterized band(s) may appear in some lysates.

물리적 형태

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
HeLa nuclear extract

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable