ABE1032

Anti-ERp57 Antibody

serum, from rabbit

• 동의어(들): Protein disulfide-isomerase A3, 58 kDa glucose-regulated protein, 58 kDa microsomal protein, p58, Disulfide isomerase ER-60, Endoplasmic reticulum resident protein 57, ER protein 57, ERp57, Endoplasmic reticulum resident protein 60, ER protein 60, ERp60
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: serum
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 종 반응성: human, rat, mouse
• 기술: ChIP: suitable; western blot: suitable
• NCBI 수납 번호: NP_005304
• UniProt 수납 번호: P30101
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... PDIA3(2923)

설명

일반 설명

Endoplasmic reticulum resident protein 57 (ERp57) is also called Protein disulfide-isomerase A3 (PDIA3), 58 kDa glucose-regulated protein (GRP58), 58 kDa microsomal protein (p58), Disulfide isomerase ER-60, and Endoplasmic reticulum resident protein 60 (ERp60). ERp57 catalyzes the rearrangement of -S-S- bonds in proteins and is associated with signal transduction, nuclear protein import and apoptosis. ERp57 is expressed in the flagellum and head regions of spermatozoa.

면역원

Recombinant protein corresponding to human ERp57.

애플리케이션

Chromatin Immunoprecipitation Analysis: A representative lot from an independent laboratory lot detected ERp57 in M14 cell lysates (Chichiarelli, S., et al. (2010). Arch Biochem Biophys. 494(2):178-183; Chichiarelli, S., et al. (2007). J Cell Physiol. 210(2):343-351.).

Western Blotting Analysis: A 1:2,000 dilution from a representative lot detected ERp57 in NPA, WRO, ARO and NCI cell lysates (Prof. F. Altieri, University of Rome, La Sapienza).

Detect ERp57 using this rabbit polyclonal antibody, Anti-ERp57 Antibody validated for use in western blotting & Chromatin IP (ChIP).

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Transcription Factors

품질

Evaluated by Western Blotting in HeLa cell lysate.

Western Blotting Analysis: 1:1,000 dilution of this antibody detected ERp57 in 10 µg of HeLa cell lysate.

표적 설명

~57 kDa observed

물리적 형태

Rabbit polyclonal in buffer containing serum with 0.05% sodium azide.

Unpurified

저장 및 안정성

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 1