ABC349
Anti-ABCA7 Antibody
from rabbit, purified by affinity chromatography
동의어(들):
ATP-binding Cassette Sub-family A (ABC1) member 7, ABC1, ABC Transporter 1, ATP-binding Cassette 1, ATP-binding Cassette Transporter 1, CERP, ABCA-SSN, Autoantigen SS-N, Macrophage ABC transporter, ABCA7
로그인조직 및 계약 가격 보기
모든 사진(2)
About This Item
UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41
추천 제품
생물학적 소스
rabbit
Quality Level
항체 형태
affinity isolated antibody
항체 생산 유형
primary antibodies
클론
polyclonal
정제법
affinity chromatography
종 반응성
human
기술
immunocytochemistry: suitable
western blot: suitable
UniProt 수납 번호
배송 상태
wet ice
타겟 번역 후 변형
unmodified
유전자 정보
human ... ABCA7(10347)
일반 설명
ATP-binding cassette sub-family A member 7 (ABCA7), also known as ABCA-SSN and Macrophage ABC transporter, is a full-size ABC transporter consisting of two sets of the multiple membrane-spanning domains plus the Walker motifs for the ATP interaction. It uses ATP hydrolysis to catalyze the transport of various molecules across cell membranes. ABCA7 is involved in phagocytosis by macrophages of apoptotic cells, binds to APOA1, may function in phospholipid and cholesterol efflux from cells, and may regulate cellular ceramide homeostasis during keratinocyte differentiation The high ABCA7 expression levels in peripheral leukocytes, thymus, spleen and bone marrow indicates a role in the immune system lipid homeostasis. ABCA1 is also highly expressed in fetal tissues, especially the liver.
면역원
KLH-conjugated linear peptide corresponding to human ABCA7.
애플리케이션
Anti-ABCA7 Antibody is a highly specific rabbit polyclonal antibody, that targets ABCA7 & has been tested in western blotting & ICC.
Immunocytochemistry Analysis: 5 µg/mL from a representative lot detected ABCA7 in HEK293 cells.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Apoptosis - Additional
품질
Evaluated by Western Blotting in HEK293 cell lysate.
Western Blotting Analysis: 1µg/mL of this antibody detected ABCA7 in 15 µg of HEK293 cell lysate.
Western Blotting Analysis: 1µg/mL of this antibody detected ABCA7 in 15 µg of HEK293 cell lysate.
표적 설명
~234 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 2 isoforms at ~219 kDa and ~234 kDa
물리적 형태
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
저장 및 안정성
Stable for 1 year at 2-8°C from date of receipt.
분석 메모
Control
HEK293 cell lysate
HEK293 cell lysate
기타 정보
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
면책조항
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
시험 성적서(COA)
제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.
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