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Merck
모든 사진(4)

주요 문서

ABC217

Sigma-Aldrich

Anti-GLI1 Antibody

from rabbit, purified by affinity chromatography

동의어(들):

Zinc finger protein GLI1, Glioma-associated oncogene, Oncogene GLI

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

affinity isolated antibody

항체 생산 유형

primary antibodies

클론

polyclonal

정제법

affinity chromatography

종 반응성

human, rat

기술

immunohistochemistry: suitable (paraffin)
western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

wet ice

타겟 번역 후 변형

unmodified

유전자 정보

human ... GLI1(2735)

일반 설명

Zinc finger protein GLI1 is also called Glioma-associated oncogene and Oncogene GLI. GLI1 is a transcriptional activator that regulates specific genes during normal development. GLI1 also mediates SHH signaling (and therefore cell proliferation and differentiation) and possibly is involved in craniofacial, central nervous system, gastrointestinal tract, and digital development. GLI1 is expressed in the testis, myometrium, fallopian tube, and brain.

면역원

KLH-conjugated linear peptide corresponding to the C-terminus of human GLI1.

애플리케이션

Anti-GLI1 Antibody is a highly specific rabbit polyclonal antibody, that targets Gli1 & has been tested in western blotting & IHC (Paraffin).
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Western Blotting Analysis: A 1:500 dilution from a representative lot detected GL1 in A431, HEK293, HEPG2, and PC3 cells.

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected GLI1 in human cerebellum and thalamus tissues.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected GLI1 in rat testis tissue.

품질

Evaluated by Western Blotting in A549 cell lysate.

Western Blotting Analysis: A 1:250 dilution of this antibody detected GLI1 in 10 µg of A549 cell lysate.

표적 설명

~150 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.

결합

Replaces: MABC678

물리적 형태

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

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문서 라이브러리 방문

Nicolas Jones Villarinho et al.
Cell biology international, 46(9), 1468-1479 (2022-07-12)
Replicative immortality is a key feature of cancer cells and it is maintained by the expression of telomerase, a promising target of novel therapies. Long-term telomerase inhibition can induce resistance, but the mechanisms underlying this process remain unclear. The Sonic

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