ABC151

Anti-Annexin A1, Antibody

from rabbit

• 동의어(들): Annexin A1, Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin I, Phospholipase A2 inhibitory protein, p35
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41
• 클론: polyclonal
• application: IHC; WB
• 종 반응성: human, rat, mouse
• 기술: immunohistochemistry: suitable; western blot: suitable

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: purified antibody
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 종 반응성: human, rat, mouse
• 종 반응성(상동성에 의해 예측): chimpanzee (based on 100% sequence homology), bovine (based on 100% sequence homology), porcine (based on 100% sequence homology)
• 기술: immunohistochemistry: suitable; western blot: suitable
• NCBI 수납 번호: NP_000691
• UniProt 수납 번호: P04083
• 배송 상태: wet ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... ANXA1(301)

설명

일반 설명

Annexin A1 (ANXA1) is a calcium and phospholipid binding protein almost entirely restricted to microglia in the CNS. During the peripheral inflammatory response, Annexin A1 is instrumental in the phagocytosis of apoptotic leukocytes. Annexin A1 restores the ability of microglia to differentiate between apoptotic and non-apoptotic cells during inflammatory activation. Current research is geared towards using Annexin A1 as a therapeutic target in neuroinflammation. Annexin A1 has also been shown to be influential in cancer development and proliferation.

특이성

This antibody recognizes the C-terminus of Annexin A1

면역원

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human Annexin A1.

애플리케이션

Anti-Annexin A1 is an antibody targeting the Annexin A1 protein, validated for use in WB & IHC.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Western Blot Analysis: 2.0 µg/mL from a representative lot detected Annexin A1 in 10 µg of C2C12, HUVEC, and NIH/3T3 cell lysate.
Immunohistochemistry Analysis: 1:500 dilution from a representative lot detected Annexin A1 in human lung tissue.

품질

Evaluated by Western Blot in L6 cell lysate.

Western Blot Analysis: 2.0 µg/mL of this antibody detected Annexin A1 in 10 µg of L6 cell lysate.

표적 설명

~38 kDa observed

물리적 형태

Format: Purified

Protein A purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

저장 및 안정성

Stable for 1 year at 2-8°C from date of receipt.

분석 메모

Control
L6 cell lysate

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable