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Merck
모든 사진(1)

주요 문서

AB9206

Sigma-Aldrich

Anti-DARPP-32 Antibody, phosphoThr34

Chemicon®, from rabbit

동의어(들):

Anti-DARPP-32, Anti-DARPP32

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About This Item

UNSPSC 코드:
12352203
eCl@ss:
32160702
NACRES:
NA.41

생물학적 소스

rabbit

Quality Level

항체 형태

affinity purified immunoglobulin

항체 생산 유형

primary antibodies

클론

polyclonal

정제법

affinity chromatography

종 반응성

human, mouse, rat

제조업체/상표

Chemicon®

기술

western blot: suitable

NCBI 수납 번호

UniProt 수납 번호

배송 상태

dry ice

타겟 번역 후 변형

phosphorylation (pThr34)

유전자 정보

human ... PPP1R1B(84152)

특이성

Recognizes DARPP-32 phosphorylated at threonine 34 .

면역원

Epitope: phosphoThr34
Synthetic peptide from DARPP-32, phosphoThr34.

애플리케이션

Research Category
Neuroscience
Research Sub Category
Reward & Addiction

Signaling Neuroscience
This Anti-DARPP-32 Antibody, phosphoThr34 is validated for use in WB for the detection of DARPP-32.
Western blot: 1:1,000. The antibody recognizes the ~32 kD DARPP-32 protein phosphorylated at Thr34 protein in rat caudate lysate prepared from caudate slices that had been incubated in the absence and presence of forskolin. The labeling by the antibody to DARPP-32 Thr34 is markedly increased by the forskolin treatment.

Optimal working dilutions must be determined by the end user.

표적 설명

~32 kD

물리적 형태

Affinity Purified immunoglobulin. Liquid in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg per mL BSA with 50% glycerol.
ImmunoAffinity Purified

저장 및 안정성

Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

분석 메모

Control
Cultured primary neurons, rat brain lysate and human breast adenocarcinoma

기타 정보

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 2


시험 성적서(COA)

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문서 라이브러리 방문

Bruno R Souza et al.
Cellular and molecular neurobiology, 31(1), 135-143 (2010-09-15)
It is well known that dopamine imbalances are associated with many psychiatric disorders and that the dopaminergic receptor D₂ is the main target of antipsychotics. Recently it was shown that levels of two proteins implicated in dopaminergic signaling, Neuronal calcium
Ana T Simões et al.
Brain : a journal of neurology, 135(Pt 8), 2428-2439 (2012-07-31)
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Lídia Cantacorps et al.
British journal of pharmacology, 177(5), 1090-1105 (2019-11-11)
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