AB5977

Anti-Musashi-1 Antibody

Chemicon^®, from rabbit

• 동의어(들): Musashi homolog 1
• UNSPSC 코드: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

속성

• 생물학적 소스: rabbit
• Quality Level: 100
• 항체 형태: affinity purified immunoglobulin
• 항체 생산 유형: primary antibodies
• 클론: polyclonal
• 정제법: affinity chromatography
• 종 반응성: rodent, mouse, rat, human
• 제조업체/상표: Chemicon^®
• 기술: immunocytochemistry: suitable; immunohistochemistry: suitable; western blot: suitable
• NCBI 수납 번호: NM_002442.2
• UniProt 수납 번호: O43347
• 배송 상태: dry ice
• 타겟 번역 후 변형: unmodified
• 유전자 정보: human ... MSI1(4440)

설명

일반 설명

In mammals, the Musashi family is important for cell fate determination, playing roles in maintenance of the stem-cell state, differentiation and tumorigenesis. Musashi1 (also known as Msi1), is selectivley expressed in neural progenitor cells, including neural stem cells. Outside the nervous system, Musashi1 is a selective marker for intestinal stem or early lineage cells. Musashi1 interacts with the Notch pathway during asymmetric cell division by binding the 3′ UTR of Numb. Numb is prevented from repressing Notch signaling when Musashi1 is present.

특이성

Reactivity with other species has not been confirmed.

Recognizes Musashi-1.

면역원

Synthetic peptide, amino acids 5-21 of Musashi.

애플리케이션

Detect Musashi-1 using this Anti-Musashi-1 Antibody validated for use in IC, IH & WB.

Immunohistochemistry:
1:200-1:1,000 dilution from a previous lot was used.

Immunocytochemistry:
1:200-1:1,000 dilution from a previous lot was used.

Western blot:
1:200-1:1,000 using ECL.

Optimal working dilutions must be determined by the end user.

Research Category
Neuroscience

Research Sub Category
Neuronal & Glial Markers

Developmental Neuroscience

RNA Binding Protein (RBP)

품질

Routinely evaluated by Western Blot on Human Placenta lysates.

Western Blot Analysis:
1:1000 dilution of this lot detected Musashi-1 on 10 μg of Human placenta lysates.

표적 설명

39 kDa

결합

Replaces: 03-114; 04-1041

물리적 형태

ImmunoAffinity Purified

Purified rabbit polyclonal in buffer containing a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.

저장 및 안정성

Stable for 1 year at -80ºC from date of receipt.

분석 메모

Control
Mouse cortical neural stem cells (Catalog No. SCR029).

법적 정보

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

면책조항

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable